(5-Morpholin-4-ylpentyl)amine

Base Information

• Chemical Name: (5-Morpholin-4-ylpentyl)amine
• CAS No.: 39793-32-3
• Molecular Formula: C₉H₂₀N₂O
• Molecular Weight: 172.271
• Hs Code.: 2934999090
• European Community (EC) Number: 803-962-7
• DSSTox Substance ID: DTXSID10427966
• Wikidata: Q82240723
• Mol file: 39793-32-3.mol

Synonyms:39793-32-3;(5-MORPHOLIN-4-YLPENTYL)AMINE;5-morpholin-4-ylpentan-1-amine;5-Morpholinopentan-1-amine;CHEMBRDG-BB 4011837;5-morpholinylpentylamine;5-Morpholin-4-ylpentylamine;4-MORPHOLINEPENTANAMINE;SCHEMBL5903339;5-(morpholin-4-yl)-pentylamine;DTXSID10427966;ZFJWLGSTGJGINS-UHFFFAOYSA-N;AKOS002670941;5-(MORPHOLIN-4-YL)PENTAN-1-AMINE;CS-0266477;C78193;EN300-1826775

Chemical Property of (5-Morpholin-4-ylpentyl)amine

Chemical Property:

• Vapor Pressure: 0.0107mmHg at 25°C
• Boiling Point: 262.7°C at 760 mmHg
• Flash Point: 112.7°C
• PSA: 38.49000
• Density: 0.96g/cm³
• LogP: 1.08580
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 172.157563266
• Heavy Atom Count: 12
• Complexity: 103

Purity/Quality:

99.90% ^*data from raw suppliers

5-morpholinopentan-1-amine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CCCCCN

Technology Process of (5-Morpholin-4-ylpentyl)amine

There total 8 articles about (5-Morpholin-4-ylpentyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(5-morpholinopentyl)isoindoline-1,3-dione → 5-morpholino-pentylamine (39793-32-3)

Guidance literature:

With hydrazine hydrate; In ethanol; for 2h; Reflux;

DOI:10.1039/d1sc00542a

Reference yield:

5-morpholino-pent-3-enenitrile → 5-morpholino-pentylamine (39793-32-3)

Guidance literature:

With ammonia; nickel; at 90 - 100 ℃; under 102971 Torr; Hydrogenation;

DOI:10.1021/ja01157a023

Reference yield:

1,5-dibromo-pentane (111-24-0) → 5-morpholino-pentylamine (39793-32-3)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate; N-benzyl-N,N,N-triethylammonium chloride / acetone / 24 h / 20 °C

2: triethylamine / methanol / Reflux

3: hydrazine hydrate / methanol / 4 h / Reflux

With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; hydrazine hydrate; triethylamine; In methanol; acetone;

DOI:10.1021/acschemneuro.9b00226

upstream raw materials:

(Z)-2,4-pentadienenitrile

3-(morpholin-4-yl)-pentanenitrile

δ-chlorovaleronitrile

1,5-dibromo-pentane

Downstream raw materials:

N-(5-morpholino-pentyl)-salicylamide