SALOR-INT L480355-1EA

Base Information

• Chemical Name: SALOR-INT L480355-1EA
• CAS No.: 57259-71-9
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• Mol file: 57259-71-9.mol

Synonyms:SALOR-INT L480355-1EA;1-(2-(HYDROXYMETHYL)PHENYL)ETHANOL;1-hydroxyMethyl-2-(1'-hydroxyethyl)benzene

Chemical Property of SALOR-INT L480355-1EA

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SALOR-INT L480355-1EA

There total 16 articles about SALOR-INT L480355-1EA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-acetyl-benzoic acid (577-56-0) → 1-(1-hydroxyethyl)-2-hydroxymethylbenzene (57259-71-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1007/BF00954082

Reference yield: 78.0%

3-methylphthalide (3453-64-3) → 1-(1-hydroxyethyl)-2-hydroxymethylbenzene (57259-71-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Product distribution; addition 0 deg C, then room t., 1 h; reductions of monoalkylactones;

DOI:10.1016/S0040-4020(88)90027-0

Reference yield: 65.0%

acetaldehyde (75-07-0,9002-91-9) + benzyl alcohol (100-51-6,185532-71-2) → 1-(1-hydroxyethyl)-2-hydroxymethylbenzene (57259-71-9)

Guidance literature:

benzyl alcohol; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; for 3h; Reflux;

acetaldehyde; In diethyl ether; hexane; at -78 - 20 ℃;

DOI:10.1002/chem.201704247

upstream raw materials:

2-acetyl-benzoic acid

o-bromobenzyl alcohol

acetaldehyde

3-methylphthalide

Downstream raw materials:

1-bromomethyl-2-(α-bromoethyl)benzene

2-acetylbenzaldehyde

1-mercaptomethyl-2-(α-mercaptoethyl)benzene

4-methyl-cis-2-phenyl-1,3-dithia-5,6-benzocycloheptene