4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione

Base Information

Chemical Name:4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione
CAS No.:21659-40-5
Molecular Formula:C19H15NO4
Molecular Weight:321.332
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60702230
Mol file:21659-40-5.mol

Synonyms:21659-40-5;DTXSID60702230;4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione

Suppliers and Price of 4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione

Chemical Property:

PSA：55.84000
LogP:2.34810
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:321.10010796
Heavy Atom Count:24
Complexity:538

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=CC2=CC3=C(C=C2)OCO3)C(=O)C(=O)N1CC4=CC=CC=C4

Technology Process of 4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione

There total 6 articles about 4-[(2H-1,3-Benzodioxol-5-yl)methylidene]-1-benzylpyrrolidine-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₃H₁₇NO₄

: 21659-40-5
4-benzo[1,3]dioxol-5-ylmethylene-1-benzyl-pyrrolidine-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: sodium methylate / methanol / 6 h / Reflux

2: hydrogenchloride / ethanol; water / 4 h / Reflux

With hydrogenchloride; sodium methylate; In methanol; ethanol; water;
DOI:10.1002/adsc.202100288

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 5336-41-4
methyl 1-benzyl-4,5-dioxopyrrolidine-3-carboxylate

: 21659-40-5
4-benzo[1,3]dioxol-5-ylmethylene-1-benzyl-pyrrolidine-2,3-dione

Guidance literature:: With hydrogenchloride; In ethanol; water; for 4h; Reflux;
DOI:10.1002/adsc.202100288

Reference yield:

: 100-46-9
benzylamine

: 21659-40-5
4-benzo[1,3]dioxol-5-ylmethylene-1-benzyl-pyrrolidine-2,3-dione

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol

2: sodium ethanolate

3: hydrogenchloride / ethanol

With hydrogenchloride; sodium ethanolate; In ethanol;
DOI:10.1055/s-0034-1380522