Butabindide oxalate

Base Information

• Chemical Name: Butabindide oxalate
• CAS No.: 185213-03-0
• Molecular Formula: C17H25N3O2.C2H2O4
• Molecular Weight: 393.43418
• Mol file: 185213-03-0.mol

Synonyms:[S-(R*,R*)]-1-(2-Amino-1-oxobutyl)-N-butyl-2,3-dihydro-1H-indole-2-carboxamide ethanedioate

Chemical Property of Butabindide oxalate

Chemical Property:

• Melting Point: 142 °C
• PSA: 153.52000
• LogP: 2.35910

Purity/Quality:

98%Min ^*data from raw suppliers

ButabindideOxalate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Butabindide is a potent inhibitor of cholecystokinin-inactivating peptidase/tripeptidyl peptidase 2 (CCK-inactivating peptidase/TPP-2; Ki = 7 nM). It is selective for CCK-inactivating peptidase/TPP-2 over a panel of serine proteases (Kis = >1 μM) as well as CCK receptors (Kis = >0.1 mM). Butabindide (0.1-100 μM) increases levels of CCK octapeptide (Item Nos. 24404 | 23371) in depolarized rat cerebral cortex slices. In vivo, butabindide inhibits CCK-inactivating peptidase/TPP-2 in mouse liver and brain (ID50s = 1.1 and 6.8 mg/kg, respectively). It also enhances CCK octapeptide-induced delay in gastric emptying and reduces food intake in mice.