2-[(Carboxycarbonothioyl)amino]anisole

Base Information

• Chemical Name: 2-[(Carboxycarbonothioyl)amino]anisole
• CAS No.: 7267-58-5
• Molecular Formula: C9H9NO3S
• Molecular Weight: 211.23766
• Hs Code.: 2930909899
• Mol file: 7267-58-5.mol

Synonyms:[(2-Methoxyphenyl)amino](thioxo)acetic acid;2-[(Carboxycarbonothioyl)amino]anisole

Chemical Property of 2-[(Carboxycarbonothioyl)amino]anisole

Chemical Property:

• PSA: 90.65000
• LogP: 1.59210

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(Carboxycarbonothioyl)amino]anisole

There total 5 articles about 2-[(Carboxycarbonothioyl)amino]anisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-(2-methoxy-phenylamino)-2-thioxo-acetamide (328961-25-7) → 2-((2-methoxyphenyl)amino)-2-thioxoacetic acid (7267-58-5) + 2-Carbamoyl-4-methoxy-benzothiazol (7267-29-0)

Guidance literature:

With sodium hydroxide; potassium hexacyanoferrate(III); In water;

DOI:10.1023/A:1015082318393

Reference yield:

methyl 2-((2-methoxyphenyl)amino)-2-thioxoacetate → 2-((2-methoxyphenyl)amino)-2-thioxoacetic acid (7267-58-5)

Guidance literature:

With sodium hydroxide; In ethylene glycol; for 3h;

DOI:10.3390/molecules26165009

Reference yield:

methyl 2-((2-methoxyphenyl)amino)-2-oxoacetate (113449-16-4) → 2-((2-methoxyphenyl)amino)-2-thioxoacetic acid (7267-58-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Lawessons reagent / toluene / 7 h / 75 °C

2: sodium hydroxide / ethylene glycol / 3 h

With Lawessons reagent; sodium hydroxide; In ethylene glycol; toluene;

DOI:10.3390/molecules26165009

upstream raw materials:

2-(2-methoxy-phenylamino)-2-thioxo-acetamide

2-methoxy-phenylamine

methyl 2-((2-methoxyphenyl)amino)-2-oxoacetate

Refernces

• 1、 Yarovenko, V. N.,Stoyanovich, F. M.,Zolotarskaya, O. Yu.,Chernoburova, E. I.,Zararzin, I. V.,Krayushkin, M. M.. "New approach to the synthesis of 2-carbamoylbenzothiazoles". . p. 144 - 147. Retrieved 2007/10/03.