1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol

Base Information

Chemical Name:1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol
CAS No.:291273-51-3
Molecular Formula:C₂₄H₂₅O₅P
Molecular Weight:0
Hs Code.:

Synonyms:1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol

Suppliers and Price of 1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol

There total 14 articles about 1,5-Anhydro-3-2,6-dideoxy-6-(diphenylphosphinyl)-3-O-(2-hydroxyphenyl)-D-arabino-hexitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135214-83-4
1,5-Anhydro-2-deoxy-4,6-O-(phenylmethylene)-D-arabino-hexopyranoside

: 291273-51-3
(2S,3S,4R)-2-(Diphenyl-phosphinoylmethyl)-4-(2-hydroxy-phenoxy)-tetrahydro-pyran-3-ol

Guidance literature:: Multi-step reaction with 9 steps

1.1: (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 20 °C

2.1: L-selectride / tetrahydrofuran / -78 °C

3.1: 92 percent / hydrogen / Pd_.C / methanol; acetic acid / 20 °C

4.1: 78 percent / pyridine

5.1: tetrahydrofuran / 0.5 h / 0 °C

5.2: 94 percent / NH₄Cl; H₂O₂ (30 percent) / H₂O; tetrahydrofuran / 0 °C

6.1: SOCl₂ / CH₂Cl₂

7.1: RuCl₃*3H₂O; NaIO₄ / CCl₄; acetonitrile; H₂O / 0 °C

8.1: K₂CO₃ / dimethylformamide

8.2: H₂SO₄(20 percent) / diethyl ether; CHCl₃ / 12 h

9.1: EtSH; AlCl₃ / CH₂Cl₂

With pyridine; ruthenium trichloride; sodium periodate; aluminium trichloride; thionyl chloride; oxalyl dichloride; hydrogen; L-Selectride; potassium carbonate; dimethyl sulfoxide; triethylamine; ethanethiol; palladium on activated charcoal; In tetrahydrofuran; methanol; tetrachloromethane; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; acetonitrile; 1.1: Swern oxidation;
DOI:10.1016/S0040-4039(02)00450-1

Reference yield:

: 291273-52-4
(2R,4aR,8R,8aS)-8-(2-Methoxy-phenoxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine

: 291273-51-3
(2S,3S,4R)-2-(Diphenyl-phosphinoylmethyl)-4-(2-hydroxy-phenoxy)-tetrahydro-pyran-3-ol

Guidance literature:: Multi-step reaction with 6 steps

1: 95 percent / DIBAL-H / CH₂Cl₂; toluene / 2 h / 20 °C

2: pyridine; DMAP / 10 h / 20 °C

3: tetrahydrofuran / 1 h / 20 °C

4: H₂O₂ / tetrahydrofuran; H₂O / 0.5 h

5: H₂ / Pd/C / methanol; CH₂Cl₂ / 4 h / 760.05 Torr

6: AlCl₃; EtSH / 2 h / 20 °C

With pyridine; dmap; aluminium trichloride; hydrogen; dihydrogen peroxide; diisobutylaluminium hydride; ethanethiol; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; toluene;
DOI:10.1021/ja001643h

Reference yield:

: 291273-53-5
[(2R,3S,4R)-3-Benzyloxy-4-(2-methoxy-phenoxy)-tetrahydro-pyran-2-yl]-methanol

: 291273-51-3
(2S,3S,4R)-2-(Diphenyl-phosphinoylmethyl)-4-(2-hydroxy-phenoxy)-tetrahydro-pyran-3-ol

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine; DMAP / 10 h / 20 °C

2: tetrahydrofuran / 1 h / 20 °C

3: H₂O₂ / tetrahydrofuran; H₂O / 0.5 h

4: H₂ / Pd/C / methanol; CH₂Cl₂ / 4 h / 760.05 Torr

5: AlCl₃; EtSH / 2 h / 20 °C

With pyridine; dmap; aluminium trichloride; hydrogen; dihydrogen peroxide; ethanethiol; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/ja001643h