[R-(R,S)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide

Base Information

Chemical Name:[R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide
CAS No.:21752-31-8
Molecular Formula:C5H12 N2 O3 S
Molecular Weight:180.228
Hs Code.:2925290090
Mol file:21752-31-8.mol

Synonyms:Sulfoximine,S-(3-amino-3-carboxypropyl)-S-methyl-, (R)-L- (8CI); (2S,SR)-Methionine sulfoximine;L-Methionine (R)-sulfoximine; Sulfoximine,S-(3-amino-3-carboxypropyl)-S-methyl-, [R-(R*,S*)]-

Suppliers and Price of [R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-Methionine [R]-sulfoximine
10mg
$ 305.00

TRC
L-Methionine[R]-Sulfoximine
1g
$ 1355.00

American Custom Chemicals Corporation
L-METHIONINE-[R]-SULFOXIMINE 95.00%
5MG
$ 495.48

Total 6 raw suppliers

Chemical Property of [R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide

Chemical Property:

Vapor Pressure:6.63E-06mmHg at 25°C
Melting Point:233-236°C (dec.)
Boiling Point:352.2°Cat760mmHg
Flash Point:166.8°C
PSA：112.62000
Density:1.46g/cm³
LogP:1.13070
Storage Temp.:Refrigerator
Solubility.:Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

L-Methionine [R]-sulfoximine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

General Description [R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide, also known as L-methionine sulfoximine, is a toxic amino acid derivative with the confirmed absolute configuration of (2S,SS)-2-amino-4-(S-methylsulfonimidoyl)-n-butanoic acid. It has been isolated from the seeds of *Cnestis palala* and exhibits acute toxicity, as demonstrated in studies involving beagle dogs. [R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide's structure and stereochemistry were verified through comparisons of optical rotation and IR spectroscopy with synthesized reference samples.

Technology Process of [R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide

There total 12 articles about [R-(R*,S*)]-S-(3-amino-3-carboxypropyl)-S-methylsulphoximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87141-35-3,87141-36-4
C₁₃H₁₄N₂O₅S

: 1982-67-8,15985-39-4,21056-59-7,21752-31-8,21752-32-9,121249-45-4,121249-46-5
L-methionine-R-sulfoximine

Guidance literature:: Multi-step reaction with 2 steps

1: (CH₃CO)2O / 6 h / Ambient temperature; Alternatively DCC, 3 hr, 0 deg C; 9 hr, room temp., pH 3 may also be used.

2: hydrolysis and deblocking

With acetic anhydride;
DOI:10.1016/S0040-4039(00)81684-6

Reference yield:

: 21056-59-7
L-methionine-S,R-sulfoximine

: 1982-67-8,15985-39-4,21056-59-7,21752-31-8,21752-32-9,121249-45-4,121249-46-5
L-methionine-R-sulfoximine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.5 hr, 0 deg C; 15 hr, room temp.

2: (CH₃CO)2O / 6 h / Ambient temperature; Alternatively DCC, 3 hr, 0 deg C; 9 hr, room temp., pH 3 may also be used.

3: hydrolysis and deblocking

With acetic anhydride;
DOI:10.1016/S0040-4039(00)81684-6