2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI)

Base Information

Chemical Name:2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI)
CAS No.:126330-91-4
Molecular Formula:C₆H₁₀N₂O₃
Molecular Weight:158.157
Hs Code.:
Mol file:126330-91-4.mol

Synonyms:2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI);METHYL (2R)-6-OXOPIPERAZINE-2-CARBOXYLATE;(R)-methyl 6-oxopiperazine-2-carboxylate

Suppliers and Price of 2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2r)-6-Oxo-2-piperazinecarboxylicAcidMethylEster
100mg
$ 285.00

Crysdot
(R)-Methyl6-oxopiperazine-2-carboxylate 95+%
1g
$ 559.00

Chemenu
(R)-Methyl6-oxopiperazine-2-carboxylate 95%
1g
$ 528.00

Alichem
(2R)-6-Oxo-2-piperazinecarboxylicacidmethylester
5g
$ 1788.22

Alichem
(2R)-6-Oxo-2-piperazinecarboxylicacidmethylester
1g
$ 535.02

Alichem
(2R)-6-Oxo-2-piperazinecarboxylicacidmethylester
250mg
$ 194.93

Total 1 raw suppliers

Chemical Property of 2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI)

Chemical Property:

Melting Point:137-145 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
Boiling Point:348.2±42.0 °C(Predicted)
PKA:13.58±0.40(Predicted)
PSA：70.92000
Density:1.192±0.06 g/cm3(Predicted)
LogP:-1.14790

Purity/Quality:: (2r)-6-Oxo-2-piperazinecarboxylicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI)

There total 2 articles about 2-Piperazinecarboxylicacid,6-oxo-,methylester,(2R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 126330-92-5
3-amino-N-[(benzyloxy)carbonyl]-D-alanine methyl ester

: 96-32-2
bromoacetic acid methyl ester

: 126330-91-4,234109-21-8
Methyl (R)-6-oxopiperazine-2-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; Yield given. Multistep reaction; 1.) THF, 2.) EtOH;
DOI:10.1002/hlca.19890720522

Reference yield:

: 126330-91-4,234109-21-8
Methyl (R)-6-oxopiperazine-2-carboxylate

Guidance literature:

Reference yield:

: 126330-91-4,234109-21-8
Methyl (R)-6-oxopiperazine-2-carboxylate

: 405175-79-3
(R)-4-((benzyloxy)carbonyl)piperazine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: iPr₂NEt / CH₂Cl₂

2: BH₃ / tetrahydrofuran

With borane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; 1: Acylation / 2: Reduction;
DOI:10.1021/jm990418b