2-CHLORO-6-FLUORO-BENZAMIDINE HYDROCHLORIDE

Base Information

• Chemical Name: 2-CHLORO-6-FLUORO-BENZAMIDINE HYDROCHLORIDE
• CAS No.: 1170884-07-7
• Molecular Formula: C7H7Cl2FN2
• Molecular Weight: 209.05
• Mol file: 1170884-07-7.mol

Synonyms:2-CHLORO-6-FLUORO-BENZAMIDINE HCL;2-CHLORO-6-FLUORO-BENZAMIDINE HYDROCHLORIDE

Chemical Property of 2-CHLORO-6-FLUORO-BENZAMIDINE HYDROCHLORIDE

Chemical Property:

• PSA: 49.87000
• LogP: 3.36520
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-6-fluoro-benzamidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-6-FLUORO-BENZAMIDINE HYDROCHLORIDE

There total 1 articles about 2-CHLORO-6-FLUORO-BENZAMIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-6-fluorobenzonitrile (668-45-1) → 2-chloro-6-fluorobenzimidamide hydrochloride (1170884-07-7)

Guidance literature:

2-chloro-6-fluorobenzonitrile; With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; isopropyl alcohol; at 0 ℃; for 12.25h;

Reference yield:

2-bromo-1-(6-bromopyridin-3-yl)ethanone (136592-20-6) + 2-chloro-6-fluorobenzimidamide hydrochloride (1170884-07-7) → 2-bromo-5-[2-(2-chloro-6-fluorophenyl)-1H-imidazol-4-yl]pyridine (1254170-77-8)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; water; at 70 ℃; Sealed tube;

Reference yield:

2-(2-bromoacetyl)-5-bromothiophene (10531-44-9) + 2-chloro-6-fluorobenzimidamide hydrochloride (1170884-07-7) → 4-(5-bromothiophen-2-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole (1254171-26-0)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; water; at 70 ℃; for 12h;

upstream raw materials:

2-chloro-6-fluorobenzonitrile

Downstream raw materials:

5-(2-(2-chloro-6-fluorophenyl)-1H-imidazol-4-yl)-2-phenylpyrimidine

4-(5-bromothiophen-2-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole

2-bromo-5-[2-(2-chloro-6-fluorophenyl)-1H-imidazol-4-yl]pyridine

methyl 2-(2-(2-chloro-6-fluorophenyl)-1H-imidazol-4-yl)benzofuran-5-carboxylate

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