[R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt

Base Information

• Chemical Name: [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt
• CAS No.: 103634-10-2
• Molecular Formula: C45H67NO7P
• Molecular Weight: 763.995
• Mol file: 103634-10-2.mol

Synonyms:[R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt;(7R,17Z)-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt;[R-(Z)]-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[(triphenylmethoxy)methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium inner salt 4-oxide

Chemical Property of [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt

Chemical Property:

• PSA: 103.93000
• LogP: 11.22240
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Methanol, Tetrahydrofuran

Purity/Quality:

97% ^*data from raw suppliers

[R-(Z)]-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[(triphenylmethoxy)methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium4-OxideInnerSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the synthesis of glycerophospholipids act as regulators of various enzyme activities

Technology Process of [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt

There total 6 articles about [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1-O-trityl-sn-glycero-3-phosphocholine (103675-56-5) + oleoylimidazole (64833-92-7) → 1-trityl-2-(octadec-cis-9-enoyl)-sn-glycero-3-phosphocholine (103634-10-2)

Guidance literature:

With sodium; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

Reference yield:

L-glycero-3-phosphorylcholine (28319-77-9,563-24-6) → 1-trityl-2-(octadec-cis-9-enoyl)-sn-glycero-3-phosphocholine (103634-10-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / ZnCl₂ / dimethylformamide / 10 h / 5 °C

2: 81 percent / sodium / dimethylsulfoxide / 0.5 h / 20 °C

With sodium; zinc(II) chloride; In dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

cis-Octadecenoic acid (112-80-1,2027-47-6) → 1-trityl-2-(octadec-cis-9-enoyl)-sn-glycero-3-phosphocholine (103634-10-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.75 h / 20 °C

2: 81 percent / sodium / dimethylsulfoxide / 0.5 h / 20 °C

With sodium; In tetrahydrofuran; dimethyl sulfoxide;

upstream raw materials:

1-O-trityl-sn-glycero-3-phosphocholine

oleoylimidazole

cis-Octadecenoic acid

L-glycero-3-phosphorylcholine

Downstream raw materials:

2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine