6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde

Base Information

Chemical Name:6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde
CAS No.:564443-27-2
Molecular Formula:C7H3F3N2OS
Molecular Weight:220.175
Hs Code.:2934100090
DSSTox Substance ID:DTXSID70396048
Wikidata:Q82196519
Mol file:564443-27-2.mol

Synonyms:564443-27-2;6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde;6-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde;6-trifluoromethyl-imidazo[2,1-b]thiazole-5-carbaldehyde;6-(Trifluoromethyl)imidazo-[2,1-b]thiazole-5-carbaldehyde;SCHEMBL1398900;DTXSID70396048;MFCD05179682;AKOS016842529;DS-1967;N13195

Suppliers and Price of 6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde
50mg
$ 155.00

Matrix Scientific
6-(Trifluoromethyl)imidazo-[2,1-b]thiazole-5-carbaldehyde 95+%
250mg
$ 468.00

Matrix Scientific
6-(Trifluoromethyl)imidazo-[2,1-b]thiazole-5-carbaldehyde 95+%
1g
$ 1170.00

Crysdot
6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde 98%
5g
$ 1188.00

Crysdot
6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde 98%
1g
$ 296.00

Chemenu
6-(trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde 95+%
100mg
$ 124.00

Chemenu
6-(trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde 95+%
250mg
$ 178.00

Chemenu
6-(trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde 95+%
5g
$ 2139.00

Chemenu
6-(trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde 95+%
1g
$ 533.00

American Custom Chemicals Corporation
6-TRIFLUOROMETHYL-IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE 95.00%
5MG
$ 500.65

Total 10 raw suppliers

Chemical Property of 6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde

Chemical Property:

PSA：62.61000
Density:1.69g/cm³
LogP:2.22710
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:219.99181838
Heavy Atom Count:14
Complexity:248

Purity/Quality:

97% ^*data from raw suppliers

6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC2=NC(=C(N21)C=O)C(F)(F)F

Technology Process of 6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde

There total 2 articles about 6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 109113-98-6
6-trifluoromethylimidazo<2,1-b>thiazole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 564443-27-2
6-(trifluoromethyl)imidazo[2,1-b]thiazol-5-carbaldehyde

Guidance literature:: N,N-dimethyl-formamide; With trichlorophosphate; In chloroform; at 0 - 5 ℃;

6-trifluoromethylimidazo<2,1-b>thiazole; In chloroform; at 20 ℃; Reflux;

With water; Cooling with ice;
DOI:10.1002/cmdc.201000346

Reference yield:

: BrH*C₆H₅F₃N₂OS

: 564443-27-2
6-(trifluoromethyl)imidazo[2,1-b]thiazol-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / water / 1 h / Reflux

2.1: trichlorophosphate / chloroform / 0 - 5 °C

2.2: 20 °C / Reflux

2.3: Cooling with ice

With hydrogenchloride; trichlorophosphate; In chloroform; water; 2.1: Vilsmeier formylation / 2.2: Vilsmeier formylation / 2.3: Vilsmeier formylation;
DOI:10.1002/cmdc.201000346