1-(1H-Benzimidazol-2-yl)propan-1-ol

Base Information

Chemical Name:1-(1H-Benzimidazol-2-yl)propan-1-ol
CAS No.:4857-00-5
Molecular Formula:C10H12N2O
Molecular Weight:176.22
Hs Code.:
DSSTox Substance ID:DTXSID70586083
Mol file:4857-00-5.mol

Synonyms:4857-00-5;1-(1H-Benzimidazol-2-yl)propan-1-ol;1-(1H-1,3-benzodiazol-2-yl)propan-1-ol;1H-Benzimidazole-2-methanol,alpha-ethyl-(9CI);1-(1H-benzo[d]imidazol-2-yl)propan-1-ol;F2101-0041;2-alpha-hydroxypropylbenzimidazole;DTXSID70586083;STL482090;AKOS000272597;AKOS016040870;MCULE-9343267448;EN300-238016;Z237599196

Suppliers and Price of 1-(1H-Benzimidazol-2-yl)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(1H-Benzimidazol-2-yl)propan-1-ol
50mg
$ 90.00

American Custom Chemicals Corporation
1-(1H-1,3-BENZODIAZOL-2-YL)PROPAN-1-OL 95.00%
5MG
$ 499.57

Total 5 raw suppliers

Chemical Property of 1-(1H-Benzimidazol-2-yl)propan-1-ol

Chemical Property:

PSA：48.91000
LogP:2.00630
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:174

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-(1H-Benzimidazol-2-yl)propan-1-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=NC2=CC=CC=C2N1)O

Technology Process of 1-(1H-Benzimidazol-2-yl)propan-1-ol

There total 1 articles about 1-(1H-Benzimidazol-2-yl)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 600-15-7,565-70-8
2-Hydroxybutanoic acid

: 4857-00-5
2-(α-hydroxypropyl) benzimidazole

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja01250a019

Reference yield: 48.0%

: 4857-00-5
2-(α-hydroxypropyl) benzimidazole

: 74126-96-8
2-propionylbenzimidazole

Guidance literature:: With manganese(IV) oxide;

Reference yield:

: 4857-00-5
2-(α-hydroxypropyl) benzimidazole

: 76098-97-0
C₁₃H₁₄N₂O₂

Guidance literature:: Multi-step reaction with 4 steps

1: 48 percent / MnO₂

2: 1.) sodium hydride / 1.) rt, 30 min, DMF; 2.) 120 deg C, 6 days

3: aq. HCl; dioxane / 1.5 h / Ambient temperature

4: 42 percent / para-toluenesulfonic acid / toluene / 0.33 h / Heating

With manganese(IV) oxide; sodium hydride; toluene-4-sulfonic acid; In 1,4-dioxane; hydrogenchloride; toluene;