Technology Process of 10β-Methyloxecane-2,4-dione
There total 8 articles about 10β-Methyloxecane-2,4-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; toluene-4-sulfonic acid;
In
acetone;
at 20 ℃;
for 6h;
DOI:10.1021/jo034049+
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 83 percent / p-TsOH*H2O / benzene / 8 h / 90 °C
2: 94 percent / aq. LiOH / tetrahydrofuran / 0 - 20 °C
3: 67 percent / PPH3; DIAD / diethyl ether / 12 h / 20 °C
4: 90 percent / H2; quinoline / Pd/CaCO3 / hexane; ethanol / 1 h / 760 Torr
5: 435 mg / Grubbs ruthenium catalyst / benzene / 10 h / Heating
6: 395 mg / H2 / Pd/C / ethanol / 8 h / 1551.44 Torr
7: 91 percent / p-TsOH; H2O / acetone / 6 h / 20 °C
With
quinoline; lithium hydroxide; di-isopropyl azodicarboxylate; water; hydrogen; toluene-4-sulfonic acid; triphenylphosphine;
palladium on activated charcoal; Lindlar's catalyst; Grubbs catalyst first generation;
In
tetrahydrofuran; diethyl ether; ethanol; hexane; acetone; benzene;
3: Mitsunobu reaction;
DOI:10.1021/jo034049+
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 94 percent / aq. LiOH / tetrahydrofuran / 0 - 20 °C
2: 67 percent / PPH3; DIAD / diethyl ether / 12 h / 20 °C
3: 90 percent / H2; quinoline / Pd/CaCO3 / hexane; ethanol / 1 h / 760 Torr
4: 435 mg / Grubbs ruthenium catalyst / benzene / 10 h / Heating
5: 395 mg / H2 / Pd/C / ethanol / 8 h / 1551.44 Torr
6: 91 percent / p-TsOH; H2O / acetone / 6 h / 20 °C
With
quinoline; lithium hydroxide; di-isopropyl azodicarboxylate; water; hydrogen; toluene-4-sulfonic acid; triphenylphosphine;
palladium on activated charcoal; Lindlar's catalyst; Grubbs catalyst first generation;
In
tetrahydrofuran; diethyl ether; ethanol; hexane; acetone; benzene;
2: Mitsunobu reaction;
DOI:10.1021/jo034049+
