3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside

Base Information

Chemical Name:3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside
CAS No.:81703-98-2
Molecular Formula:C33H39NO13
Molecular Weight:657.6617
Hs Code.:

3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside

Synonyms:

Suppliers and Price of 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside

Chemical Property:

Vapor Pressure:8.73E-32mmHg at 25°C
Boiling Point:863.3°Cat760mmHg
Flash Point:475.9°C
Density:1.53g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside

There total 19 articles about 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxyhexopyranosyl)hexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 81661-55-4
7-O-<4-O-(3,4-di-O-acetyl-2,6-didesoxy-α-L-lyxo-hexopyranosyl)-2,3,6-tridesoxy-3-(trifluoroacetamido)-α-L-lyxo-hexopyranosyl>daunomycinone

: 81703-98-2,67441-26-3
7-<3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexopyranosyl>daunomycinone

Guidance literature:: With sodium hydroxide; In various solvent(s); at 0 ℃; for 7h;
DOI:10.1016/S0008-6215(00)80810-1

Reference yield: 89.0%

: 82225-08-9
7-O-<4-O-(2,6-didesoxy-α-L-lyxo-hexopyranosyl)-2,3,6-tridesoxy-3-(trifluoroacetamido)-α-L-lyxo-hexopyranosyl>daunomycinone

: 81703-98-2,67441-26-3
7-<3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexopyranosyl>daunomycinone

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 5h;
DOI:10.1016/0040-4020(81)85015-6

Reference yield:

: 64605-19-2
3,4-di-O-acetyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl chloride

: 81703-98-2,67441-26-3
7-<3-amino-2,3,6-trideoxy-4-O-(2,6-dideoxy-α-L-lyxo-hexopyranosyl)-α-L-lyxo-hexopyranosyl>daunomycinone

Guidance literature:: Multi-step reaction with 5 steps

1: 72 percent / mercuric bromide, yellow mecuric oxide / 30 h

2: 78 percent / hydrogen / 10percent palladium-on-charcoal / ethanol

3: 100 percent / pyridine / 0 °C

4: 57 percent / tin tetrachloride / CH₂Cl₂ / 0.75 h / Ambient temperature

5: 100 percent / 0.1M NaOH / various solvent(s) / 7 h / 0 °C

With pyridine; sodium hydroxide; hydrogen; tin(IV) chloride; mercury dibromide; mercury(II) oxide; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1016/S0008-6215(00)80810-1