2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione

Base Information

Chemical Name:2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione
CAS No.:6914-99-4
Molecular Formula:C18H11NO3
Molecular Weight:289.28
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70353575
Nikkaji Number:J2.686.788F
Wikidata:Q82131241
ChEMBL ID:CHEMBL1419229
Mol file:6914-99-4.mol

Synonyms:2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione;6914-99-4;AKOS BBS-00007408;2-(4-hydroxyphenyl)benzo[de]isoquinoline-1,3-dione;C18H11NO3;Oprea1_103202;Oprea1_488017;MLS001207606;IFLab1_000277;2-(4-Hydroxy-phenyl)-benzo-[de]isoquinoline-1,3-dione;CHEMBL1419229;SCHEMBL10792923;DTXSID70353575;HMS1412M13;HMS2828F11;AKOS000273525;IDI1_008496;N-(4-hydroxyphenyl)-1,8-naphthalimide;SMR000513783;EN300-235923;BRD-K47992308-001-07-2;Z56756227;F0013-1087;3-(4-hydroxyphenyl)-3-azatricyclo[7.3.1.0,5,13]trideca-1(13),5,7,9,11-pentaene-2,4-dione;3-(4-hydroxyphenyl)-3-azatricyclo[7.3.1.0?,??]trideca-1(13),5,7,9,11-pentaene-2,4-dione

Suppliers and Price of 2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(4-Hydroxy-phenyl)-benzo-[de]isoquinoline-1,3-dione 95%+
1g
$ 436.00

Matrix Scientific
2-(4-Hydroxy-phenyl)-benzo-[de]isoquinoline-1,3-dione 95%+
5g
$ 1442.00

Matrix Scientific
2-(4-Hydroxy-phenyl)-benzo-[de]isoquinoline-1,3-dione 95%+
2.500g
$ 953.00

American Custom Chemicals Corporation
2-(4-HYDROXY-PHENYL)-BENZO[DE]ISOQUINOLINE-1,3-DIONE 95.00%
5MG
$ 496.89

Total 6 raw suppliers

Chemical Property of 2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione

Chemical Property:

PSA：59.30000
LogP:2.64750
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:289.07389321
Heavy Atom Count:22
Complexity:439

Purity/Quality:

NLT 98% ^*data from raw suppliers

2-(4-Hydroxy-phenyl)-benzo-[de]isoquinoline-1,3-dione 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)C4=CC=C(C=C4)O

Technology Process of 2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione

There total 2 articles about 2-(4-Hydroxy-phenyl)-benzo[de]isoquinoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 81-84-5
1,8-Naphthalic anhydride

: 123-30-8
4-amino-phenol

: 6914-99-4
2-(4-hydroxyphenyl) -1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: In 2-ethoxy-ethanol; at 120 ℃;
DOI:10.1002/chem.201902882

Reference yield:

: 6914-99-4
2-(4-hydroxyphenyl) -1H-benzo[de]isoquinoline-1,3(2H)-dione

Guidance literature:: Naphthalsaeureanhydrid, p-OH-C6H4-NH2, in DMA, Δ;

Reference yield:

: 6914-99-4
2-(4-hydroxyphenyl) -1H-benzo[de]isoquinoline-1,3(2H)-dione

: 954497-51-9
C₁₉H₁₁NO₃

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / toluene / 4 h / Inert atmosphere; Reflux

2: acetonitrile / 20 °C / Inert atmosphere

3: Irradiation

With potassium carbonate; In toluene; acetonitrile; 1: Mannich reaction;
DOI:10.1021/jo102531f