1-Dehydro Epiandrosterone

Base Information

• Chemical Name: 1-Dehydro Epiandrosterone
• CAS No.: 23633-63-8
• Molecular Formula: C₁₉H₂₈O₂
• Molecular Weight: 288.43
• Mol file: 23633-63-8.mol

Synonyms:1-Dehydro Epiandrosterone;1-Androsterone

Chemical Property of 1-Dehydro Epiandrosterone

Chemical Property:

• Melting Point: 169-171 °C
• Boiling Point: 416.2±45.0 °C(Predicted)
• PKA: 14.32±0.60(Predicted)
• PSA: 37.30000
• Density: 1.105±0.06 g/cm3(Predicted)
• LogP: 3.73510

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Dehydroepiandrosterone is an androsterone metabolite. Suitable for the detection of steroid abuse screenings.

Technology Process of 1-Dehydro Epiandrosterone

There total 4 articles about 1-Dehydro Epiandrosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-beta-hydroxy-5-alpha-androst-1-en-17-one (19671-47-7,23633-63-8,33805-57-1,38859-37-9,76822-24-7)

Guidance literature:

entspr. 2-THP-Ether-17-acetat, Hydrolyse d. Estergruppe, Ox. d. 17-ols mit CrO3/Pyridin, Spaltung d. 3-THP-Ethers;

Reference yield:

5α-androst-1-ene-3,17-dione (571-40-4) → 3α-hydroxy-5α-androst-1-en-17-one + 5α-androst-1-en-3β-ol-17-one (23633-63-8)

Guidance literature:

With lithium tri-sec-butyl(hydrido)borate; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1h; optical yield given as %de;

DOI:10.1016/j.steroids.2011.02.001

Reference yield:

(5α,17β)-3-oxoandrost-1-en-17-yl acetate (64-82-4,6656-41-3,21507-42-6,25615-33-2,54631-35-5,79732-37-9,97413-69-9) → 5α-androst-1-en-3β-ol-17-one (23633-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Li

With lithium tri-t-butoxyaluminum hydride;

DOI:10.1002/cber.19660990406

upstream raw materials:

(3β,5α,17β)-3-hydroxyandrost-1-en-17-yl acetate

(5α,17β)-3-oxoandrost-1-en-17-yl acetate

5α-androst-1-ene-3,17-dione