2-(2-NITRO-ETHYL)-FURAN

Base Information

• Chemical Name: 2-(2-NITRO-ETHYL)-FURAN
• CAS No.: 5462-90-8
• Molecular Formula: C6H7 N O3
• Molecular Weight: 141.12
• Hs Code.: 2932190090
• Mol file: 5462-90-8.mol

Synonyms:2-(2-Nitroethyl)furan;NSC 16180

Chemical Property of 2-(2-NITRO-ETHYL)-FURAN

Chemical Property:

• Vapor Pressure: 0.0557mmHg at 25°C
• Boiling Point: 233.5°C at 760 mmHg
• Flash Point: 95°C
• PSA: 58.96000
• Density: 1.197g/cm³
• LogP: 1.62200

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-NITRO-ETHYL)-FURAN

There total 11 articles about 2-(2-NITRO-ETHYL)-FURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-(2-nitrovinyl)furan (699-18-3,32782-45-9) → 2-(2-nitroethyl)furan (5462-90-8)

Guidance literature:

With formic acid; ethanol; C₁₉H₂₆ClIrN₃O⁽¹⁺⁾*Cl^(1-); In water; at 80 ℃; chemoselective reaction;

DOI:10.1039/d1gc01907d

Reference yield: 93.0%

2-[(E)-2-nitroethenyl]furan (699-18-3,32782-45-9) → 2-(2-nitroethyl)furan (5462-90-8)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; silica gel; In benzene; at 60 ℃; for 20h;

DOI:10.1246/cl.1985.523

Reference yield: 92.0%

1-(furan-2-yl)-2-nitroethanol (52239-33-5) → 2-(2-nitroethyl)furan (5462-90-8)

Guidance literature:

With tri-n-butyl-tin hydride; In water; at 80 ℃; for 0.0833333h; Microwave irradiation; Green chemistry;

DOI:10.1080/00397911.2014.926373

upstream raw materials:

2-(2-nitrovinyl)furan

furan

1-nitroethylene

furfural

Downstream raw materials:

Toluene-4-sulfonic acid 2-bromo-6-[2-(2,5-dimethyl-pyrrol-1-yl)-3-furan-2-yl-propyl]-4-methoxy-phenyl ester

Toluene-4-sulfonic acid 2-bromo-6-((E)-3-furan-2-yl-2-nitro-propenyl)-4-methoxy-phenyl ester

Toluene-4-sulfonic acid 2-(2-amino-3-furan-2-yl-propyl)-6-bromo-4-methoxy-phenyl ester

4-(furan-2-yl)-3-oxobutanoic acid ethyl ester

Refernces

• 1、 Chen, Yang,Liu, Changmeng,Xu, Dong,Xu, Jiaxi,Yang, Zhanhui. "Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water". supporting information. p. 6050 - 6058. Retrieved 2021/08/23.
• 2、 Chandrasekhar, Sosale,Shrinidhi, Annadka. "Useful extensions of the henry reaction: Expeditious routes to nitroalkanes and nitroalkenes in aqueous media". . p. 3008 - 3018. Retrieved 2014/10/16.