Ethyl 2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate

Base Information

• Chemical Name: Ethyl 2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate
• CAS No.: 61202-99-1
• Molecular Formula: C₉H₁₂O₅
• Molecular Weight: 200.191
• Hs Code.: 2932999099
• Mol file: 61202-99-1.mol

Synonyms:Ethyl 2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate;(E)-ethyl 2-hydroxy-2-(2-oxo-dihydro-2H-pyran-3(4H)-ylidene)acetate

Chemical Property of Ethyl 2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate

Chemical Property:

• Boiling Point: 366.7±31.0 °C(Predicted)
• PKA: 9.47±0.20(Predicted)
• PSA: 69.67000
• Density: 1.237±0.06 g/cm3(Predicted)
• LogP: 0.07180
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate

There total 1 articles about Ethyl 2-oxo-2-(2-oxotetrahydro-2H-pyran-3-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3,4,5,6-tetrahydro-2H-pyran-2-one (542-28-9,26354-94-9) + oxalic acid diethyl ester (95-92-1) → ethyl 2-oxo-2-(2-oxooxan-3-yl)acetate (61202-99-1)

Guidance literature:

With ethanol; sodium; 1.) 0 deg C, 1 h, 2.) r.t., 20 h;

DOI:10.1002/ardp.19933261206

Reference yield: 78.0%

5-(N-Methyl-hydrazino)-2-phenyl-2H-pyridazin-3-one (98767-49-8) + ethyl 2-oxo-2-(2-oxooxan-3-yl)acetate (61202-99-1) → [N'-Methyl-N'-(6-oxo-1-phenyl-1,6-dihydro-pyridazin-4-yl)-hydrazino]-[2-oxo-dihydro-pyran-(3Z)-ylidene]-acetic acid ethyl ester

Guidance literature:

In acetic acid; for 168h; Ambient temperature;

Reference yield: 55.0%

4-Bromo-5-(N-methyl-hydrazino)-2-phenyl-2H-pyridazin-3-one (128457-11-4) + ethyl 2-oxo-2-(2-oxooxan-3-yl)acetate (61202-99-1) → C20H20N4O5

Guidance literature:

In acetic acid; for 72h; Ambient temperature;

upstream raw materials:

3,4,5,6-tetrahydro-2H-pyran-2-one

oxalic acid diethyl ester

Downstream raw materials:

3-(4-Fluorphenylhydrazono)-5,6-dihydro-pyran-2(4H)-on