N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE

Base Information

• Chemical Name: N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
• CAS No.: 218796-15-7
• Molecular Formula: C8H6ClFN2O3
• Molecular Weight: 232.599
• Hs Code.: 2924297099
• Mol file: 218796-15-7.mol

Synonyms:N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE;N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide

Chemical Property of N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE

Chemical Property:

• PSA: 78.41000
• LogP: 3.51840
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

N1-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE

There total 2 articles about N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

N-(2-chloro-6-fluorophenyl)acetamide (343-73-7) → N-(2-chloro-6-fluoro-3-nitrophenyl)acetamide (218796-15-7)

Guidance literature:

With sodium nitrate; sulfuric acid; In water; at -10 - 24 ℃; for 12.5h;

Reference yield:

2-chloro-6-fluoroaniline (363-51-9) → N-(2-chloro-6-fluoro-3-nitrophenyl)acetamide (218796-15-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 1 h / 90 °C

2: nitric acid; sulfuric acid / 0 - 20 °C

With sulfuric acid; nitric acid; acetic acid;

Reference yield: 72.0%

N-(2-chloro-6-fluoro-3-nitrophenyl)acetamide (218796-15-7) → N-(3-amino-2-chloro-6-fluorophenyl)acetamide (1383745-38-7)

Guidance literature:

With hydrogenchloride; iron; ammonium chloride; In ethanol; water; at 60 ℃; for 8h;

upstream raw materials:

2-chloro-6-fluoroaniline

N-(2-chloro-6-fluorophenyl)acetamide

Downstream raw materials:

C₂₅H₂₅ClFN₇O₃S

C₁₈H₁₃ClFN₅O₄S

N-(3-amino-2-chloro-6-fluorophenyl)acetamide

C₁₂H₁₀ClFN₂O₄S

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