1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid

Base Information

• Chemical Name: 1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid
• CAS No.: 1246553-28-5
• Molecular Formula: C₁₀H₁₆N₂O₅
• Molecular Weight: 244.247
• Hs Code.: 2933599090
• Mol file: 1246553-28-5.mol

Synonyms:1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid;1-Boc-5-oxo-piperazine-2-carboxylic acid

Chemical Property of 1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid

Chemical Property:

• Melting Point: 165-175°C
• Boiling Point: 481.0±45.0 °C(Predicted)
• PKA: 3.35±0.20(Predicted)
• PSA: 99.43000
• Density: 1.289±0.06 g/cm3(Predicted)
• LogP: 0.02030
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

95+% ^*data from raw suppliers

1-[(2-Methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-[(2-Methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic Acid is sued in preparation of Heterocyclic compounds; used in the treatment of kinetoplastid infection.

Technology Process of 1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid

There total 2 articles about 1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

di-tert-butyl dicarbonate (24424-99-5) + (S)-5-oxo-piperazine-2-carboxylic acid methyl ester (1191885-41-2) → (S)-5-oxopiperazine-1,2-dicarboxylic acid 1-tert-butyl ester (1033713-11-9,1246553-28-5)

Guidance literature:

(S)-5-oxo-piperazine-2-carboxylic acid methyl ester; With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃;

di-tert-butyl dicarbonate; In 1,4-dioxane; water; at 0 - 20 ℃; for 16h;

With potassium hydrogensulfate; In 1,4-dioxane; water; pH=3;

DOI:10.1021/jo901389q

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + (R)-5-oxo-piperazine-2-carboxylic acid methyl ester (1212103-36-0) → (R)-5-oxopiperazine-1,2-dicarboxylic acid 1-tert-butyl ester (1191885-45-6,1246553-28-5)

Guidance literature:

(R)-5-oxo-piperazine-2-carboxylic acid methyl ester; With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃;

di-tert-butyl dicarbonate; In 1,4-dioxane; water; at 0 - 20 ℃; for 16h;

With potassium hydrogensulfate; In 1,4-dioxane; water; pH=3;

DOI:10.1021/jo901389q

upstream raw materials:

di-tert-butyl dicarbonate

(S)-5-oxo-piperazine-2-carboxylic acid methyl ester

(R)-5-oxo-piperazine-2-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1246553-28-5 1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send