N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide

Base Information

Chemical Name:N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide
CAS No.:448233-17-8
Molecular Formula:C8H8F3N3O
Molecular Weight:219.166
Hs Code.:2928000090
DSSTox Substance ID:DTXSID30380625
Wikidata:Q82170959
ChEMBL ID:CHEMBL1602349
Mol file:448233-17-8.mol

Synonyms:448233-17-8;N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide;N-(3-(Trifluoromethyl)phenyl)hydrazinecarboxamide;1-amino-3-[3-(trifluoromethyl)phenyl]urea;3-amino-1-[3-(trifluoromethyl)phenyl]urea;n-[3-(trifluoromethyl)phenyl]hydrazinecarboxamide;MLS000696515;SCHEMBL966454;CHEMBL1602349;DTXSID30380625;KALJZHYDUIZASO-UHFFFAOYSA-N;HMS2738G04;MFCD01869439;AKOS002961077;SB86379;SMR000336621;9W-0814;A924604;SR-01000307083;J-522982;SR-01000307083-1

Suppliers and Price of N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[3-(Trifluoromethyl)phenyl]-1-hydrazinecarboxamide
500mg
$ 175.00

Matrix Scientific
N-[3-(Trifluoromethyl)phenyl]-1-hydrazinecarboxamide >95%
1g
$ 228.00

Matrix Scientific
N-[3-(Trifluoromethyl)phenyl]-1-hydrazinecarboxamide >95%
500mg
$ 181.00

Matrix Scientific
N-[3-(Trifluoromethyl)phenyl]-1-hydrazinecarboxamide >95%
5g
$ 524.00

Crysdot
N-(3-(Trifluoromethyl)phenyl)hydrazinecarboxamide 95+%
5g
$ 519.00

American Custom Chemicals Corporation
N-[3-(TRIFLUOROMETHYL)PHENYL]-1-HYDRAZINECARBOXAMIDE 95.00%
10G
$ 1585.35

American Custom Chemicals Corporation
N-[3-(TRIFLUOROMETHYL)PHENYL]-1-HYDRAZINECARBOXAMIDE 95.00%
5G
$ 1115.96

American Custom Chemicals Corporation
N-[3-(TRIFLUOROMETHYL)PHENYL]-1-HYDRAZINECARBOXAMIDE 95.00%
1G
$ 722.80

AK Scientific
N-[3-(Trifluoromethyl)phenyl]-1-hydrazinecarboxamide
500mg
$ 294.00

Total 3 raw suppliers

Chemical Property of N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide

Chemical Property:

Melting Point:92-98°
PKA:11.57±0.20(Predicted)
PSA：70.64000
Density:1.441±0.06 g/cm3(Predicted)
LogP:2.80540
XLogP3:1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:219.06194637
Heavy Atom Count:15
Complexity:232

Purity/Quality:

97% ^*data from raw suppliers

N-[3-(Trifluoromethyl)phenyl]-1-hydrazinecarboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)NC(=O)NN)C(F)(F)F

Technology Process of N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide

There total 3 articles about N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 329-01-1
1-isocyanato-3-trifluoromethyl-benzene

: 448233-17-8
N-(3-trifluoromethylphenyl)hydrazinecarbamide

Guidance literature:: With hydrazine hydrate; In dichloromethane; at -60 - 20 ℃;
DOI:10.1021/jm021074j

Reference yield:

: 202598-92-3
phenyl [3-(trifluoromethyl)phenyl]carbamate

: 448233-17-8
N-(3-trifluoromethylphenyl)hydrazinecarbamide

Guidance literature:: With hydrazine hydrate monohydrate; In 1,2-dimethoxyethane; at 20 ℃;
DOI:10.1021/acs.jmedchem.1c02002

Reference yield:

: 98-16-8
3-trifluoromethylaniline

: 448233-17-8
N-(3-trifluoromethylphenyl)hydrazinecarbamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1,2-dichloro-ethane / -5 °C / 11.25 Torr / Reflux

2: hydrazine hydrate monohydrate / water monomer / 4 h / Sonication

With hydrazine hydrate monohydrate; In water monomer; 1,2-dichloro-ethane;