Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate,

Base Information

Chemical Name:Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate,
CAS No.:201402-98-4
Molecular Formula:
Molecular Weight:555.7717
Hs Code.:
Mol file:201402-98-4.mol

Synonyms:2-[3-Amino-2-Hydroxy-4-(Phenyl thio)-Butyl]-N-(1,1-dimethyl ethyl) Decahydro-3-isoquinoline Carboxamide Mono Benzoate;Decahydro- 3 –Isoquinoline Carboxamide Mono Benzoate, Nelfinavir Mesylate,;Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate,

Suppliers and Price of Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate,

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate,

Chemical Property:

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate,

There total 1 articles about Decahydro-3soquinolineCarboxamideMonoBenzoate,NelfinavirMesylate, which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 108-98-5
thiophenol

: 65-85-0,8013-63-6
benzoic acid

: 201402-97-3
2-{(S)-4-[(R)-2-((3S,4aS,8aS)-3-tert-Butylcarbamoyl-octahydro-isoquinolin-2-yl)-1-hydroxy-ethyl]-4,5-dihydro-oxazol-2-yl}-benzoic acid methyl ester

: 201402-98-4
(2R,3R)-4-((3S,4aS,8aS)-3-(tertbutylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-(phenylthio)butan-2-aminium benzoate

Guidance literature:: thiophenol; 2-{(S)-4-[(R)-2-((3S,4aS,8aS)-3-tert-Butylcarbamoyl-octahydro-isoquinolin-2-yl)-1-hydroxy-ethyl]-4,5-dihydro-oxazol-2-yl}-benzoic acid methyl ester; With potassium hydrogencarbonate; In tetrahydrofuran;

With ethanolamine; Heating;

benzoic acid; In diethyl ether;
DOI:10.1016/S0040-4039(01)01338-7

Reference yield:

: 201402-98-4
(2R,3R)-4-((3S,4aS,8aS)-3-(tertbutylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-(phenylthio)butan-2-aminium benzoate

: 159989-65-8
nelfinavir mesylate

Guidance literature:: Multi-step reaction with 2 steps

1: methanol

2: methanol; dichloromethane

In methanol; dichloromethane;
DOI:10.5935/0103-5053.20150049