Amisulpride EP impurity C

Base Information

Chemical Name:Amisulpride EP impurity C
CAS No.:176849-91-5
Molecular Formula:C15H22IN3O2
Molecular Weight:403.263
Hs Code.:
European Community (EC) Number:642-255-6
Nikkaji Number:J3.600.805I

Synonyms:Amisulpride EP impurity C;176849-91-5;4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-iodo-2-methoxybenzamide;4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxy-benzamide;4-Amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-iodo-2-methoxybenzamide;Amisulpride Impurity C;BCP33562;4-Amino-N-[[(2RS)-1-ethyl-pyrrolidin-2-yl]methyl]-5-iodo-2-methoxy-benzamide;4-?Amino-?N-?[(1-?ethyl-?2-?pyrrolidinyl)?methyl]?-?5-?iodo-?2-?methoxy-benzamide;Amisulpride Imp. C (EP)

Suppliers and Price of Amisulpride EP impurity C

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Amisulpride EP impurity C

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:403.07567
Heavy Atom Count:21
Complexity:356

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)I

Technology Process of Amisulpride EP impurity C

There total 3 articles about Amisulpride EP impurity C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 176849-86-8
4-amino-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-benzamide

: 176849-91-5
4-amino-N-(1-ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide

Guidance literature:: With iodine; In chloroform;
DOI:10.1002/jlcr.450

Reference yield:

: 27492-84-8
Methyl 4-amino-2-methoxybenzoate

: 176849-91-5
4-amino-N-(1-ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: LiOH*2H₂O / tetrahydrofuran; methanol

2: DCC; HOBt

3: I₂ / CHCl₃

With lithium hydroxide; iodine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; chloroform;
DOI:10.1002/jlcr.450

Reference yield:

: 2486-80-8
4-amino-2-methoxybenzoic acid

: 176849-91-5
4-amino-N-(1-ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: DCC; HOBt

2: I₂ / CHCl₃

With iodine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In chloroform;
DOI:10.1002/jlcr.450