INDEX NAME NOT YET ASSIGNED

Base Information

• Chemical Name: INDEX NAME NOT YET ASSIGNED
• CAS No.: 795310-05-3
• Molecular Formula: C5H5N5O
• Molecular Weight: 151.1261
• Mol file: 795310-05-3.mol

Synonyms:2-Amino-3H-imidazo[1,5-a][1,3,5]triazin-4-one;5,8-diaza-7,9-dicarbaguanine;alloguanine;

Chemical Property of INDEX NAME NOT YET ASSIGNED

Chemical Property:

• PSA: 89.07000
• LogP: -0.41900

Purity/Quality:

2-amino-Imidazo[1,5-a]-1,3,5-triazin-4(3H)-one 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of INDEX NAME NOT YET ASSIGNED

There total 2 articles about INDEX NAME NOT YET ASSIGNED which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-amino-6-formylaminomethyl-1H-[1,3,5]-triazin-2-one (795310-04-2) → 2-amino-6-oxo-5,8-diaza-7,9-dicarbapurine (795310-05-3)

Guidance literature:

With sulfuric acid; at 100 ℃; for 5h;

DOI:10.1021/ol048649m

Reference yield: 85.0%

4-amino-6-[(formylamino)methyl]-1H-[1,3,5]triazin-2-one → 2-amino-6-oxo-5,8-diaza-7,9-dicarbapurine (795310-05-3)

Guidance literature:

With sulfuric acid; at 100 ℃; for 5h;

DOI:10.1002/hlca.200590150

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + (3S,4S)-3,4-dibenzoyloxy-N-chloropyrrolidine (557791-43-2) + 2-amino-6-oxo-5,8-diaza-7,9-dicarbapurine (795310-05-3) → 2-amino-6-oxo-9-[N-(tert-butyloxycarbonyl)-(3'S,4'S)-3',4'-dibenzoyloxy-(2'S)-pyrrolidinyl]-5,8-diaza-7,9-dicarbapurine + 2-amino-6-oxo-9-[N-(tert-butyloxycarbonyl)-(3'S,4'S)-3',4'-dibenzoyloxy-(2'R)-pyrrolidinyl]-5,8-diaza-7,9-dicarbapurine

Guidance literature:

(3S,4S)-3,4-dibenzoyloxy-N-chloropyrrolidine; 2-amino-6-oxo-5,8-diaza-7,9-dicarbapurine; With toluene-4-sulfonic acid; In dimethyl sulfoxide; at 20 ℃; for 6h;

di-tert-butyl dicarbonate; With triethylamine; In dichloromethane; dimethyl sulfoxide; at 20 ℃; for 2h; Title compound not separated from byproducts;

DOI:10.1021/ol048649m

upstream raw materials:

4-amino-6-formylaminomethyl-1H-[1,3,5]-triazin-2-one

Refernces

• 1、 Han, Bo,Jaun, Bernhard,Krishnamurthy, Ramanarayanan,Eschenmoser, Albert. "Mannich-type C-nucleosidations in the 5,8-diaza-7,9-dicarba-purine family". . p. 3691 - 3694. Retrieved 2007/10/03.