benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Base Information

Chemical Name:benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate
CAS No.:936901-82-5
Molecular Formula:C19H18ClIN4O2
Molecular Weight:496.735
Hs Code.:
Mol file:936901-82-5.mol

Synonyms:benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate;4-(8-Chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)-1-piperidine carboxylic acid benzyl ester

Suppliers and Price of benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BENZYL-4-(8-CHLORO-1-IODOIMIDAZO[1,5-A]PYRAZIN-3-YL)PIPERIDINE-1-CARBOXYLATE 95.00%
5MG
$ 501.19

Total 4 raw suppliers

Chemical Property of benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Chemical Property:

PSA：59.73000
Density:1.73
LogP:4.44140

Purity/Quality:

98%min ^*data from raw suppliers

BENZYL-4-(8-CHLORO-1-IODOIMIDAZO[1,5-A]PYRAZIN-3-YL)PIPERIDINE-1-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

There total 1 articles about benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 936901-81-4
benzyl 4-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

: 936901-82-5
benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Guidance literature:: With N-iodo-succinimide; In N,N-dimethyl-formamide; at 55 ℃; for 20h;

Reference yield:

: 936901-82-5
benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

: 936901-83-6
benzyl 4-(8-amino-1-iodoimidazo[1,5-a]pyrazin-3-yI)piperidine-1-carboxylate

Guidance literature:: With ammonia; In isopropyl alcohol; at -78 - 110 ℃;

Reference yield:

: 936901-82-5
benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

: benzyl 4-[8-amino-1-(1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / isopropyl alcohol / 24 h / 110 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,2-dimethoxyethane; water / 12 h / 100 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; ammonia; potassium carbonate; In 1,2-dimethoxyethane; water; isopropyl alcohol; 2: Suzuki coupling;
DOI:10.1016/j.bmcl.2011.01.139