ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

Base Information

• Chemical Name: ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate
• CAS No.: 1132610-84-4
• Molecular Formula: C11H12N2O2
• Molecular Weight: 204.22518
• Mol file: 1132610-84-4.mol

Synonyms:ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate;5-METHYL-4-AZAINDOLE-2-CARBOXYLIC ACID ETHYL ESTER

Chemical Property of ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

Chemical Property:

• Boiling Point: 355.7±37.0 °C(Predicted)
• PKA: 12.85±0.40(Predicted)
• PSA: 54.98000
• Density: 1.232±0.06 g/cm3(Predicted)
• LogP: 2.04800

Purity/Quality:

99%, ^*data from raw suppliers

5-Methyl-4-azaindole-2-carboxylicacidethylester 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

There total 3 articles about ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-(6-methyl-3-nitropyridin-2-yl)-2-oxopropanoate → 5-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester (1132610-84-4)

Guidance literature:

With iron; ammonium chloride; In tetrahydrofuran; ethanol; water; at 90 ℃; for 2h;

Reference yield:

4-dimethylamino-3-buten-2-one (1190-91-6) + 4-amino-2-ethoxycarbonyl-pyrrole (67318-12-1) → 5-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester (1132610-84-4)

Guidance literature:

at 100 ℃; for 14h;

Reference yield:

3-nitro-2,6-lutidine (15513-52-7,767567-84-0) → 5-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester (1132610-84-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium ethoxide / diethyl ether; ethanol / 0.5 h / 20 °C

1.2: 4 h / 20 °C

2.1: iron; ammonium chloride / ethanol; tetrahydrofuran; water / 2 h / 90 °C

With potassium ethoxide; iron; ammonium chloride; In tetrahydrofuran; diethyl ether; ethanol; water;

upstream raw materials:

4-dimethylamino-3-buten-2-one

4-amino-2-ethoxycarbonyl-pyrrole

3-nitro-2,6-lutidine

Downstream raw materials:

C₁₁H₁₁BrN₂O₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1132610-84-4 ethyl 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send