Cyamemazine-d6

Base Information

• Chemical Name: Cyamemazine-d6
• CAS No.: 1216608-24-0
• Molecular Formula: C₁₉H₂₁N₃S
• Molecular Weight: 329.414
• Mol file: 1216608-24-0.mol

Synonyms:Cyamemazine-d6;10-[3-(DiMethylaMino-d6)-2-Methylpropyl]-10H-phenothiazine-2-carbonitrile;2-Cyano-10-[(3-diMethylaMino-d6)-2-Methylpropyl)phenothiazine;CiaMatil-d6;Cianatil-d6;CyaMeMazin-d6;CyaMeproMazine-d6;CyaMeproMezine-d6

Chemical Property of Cyamemazine-d6

Chemical Property:

• PSA: 55.57000
• LogP: 4.42368
• Storage Temp.: Refrigerator

Purity/Quality:

97% ^*data from raw suppliers

Cyamemazine-d6 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Labelled Cyamemazine is an anxiolytic antipsychotic, which reduces ethanol withdrawal symptoms.

Technology Process of Cyamemazine-d6

There total 2 articles about Cyamemazine-d6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Desmethyl cyamemazine + d6-dimethyl sulfate (15199-43-6) → C19H15(2)H6N3S (1216608-24-0)

Guidance literature:

Desmethyl cyamemazine; d6-dimethyl sulfate; In tetrahydrofuran; at 70 ℃; for 2h;

d6-dimethyl sulfate; With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 2h; Reflux;

DOI:10.1002/jlcr.3145

Reference yield:

10-(3-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl)-10H-phenothiazine-2-carbonitrile (1590417-42-7) → C19H15(2)H6N3S (1216608-24-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrazine hydrate / ethanol / 4 h / 70 °C / Inert atmosphere

2.1: tetrahydrofuran / 2 h / 70 °C

2.2: 2 h / 0 °C / Reflux

With hydrazine hydrate; In tetrahydrofuran; ethanol;

DOI:10.1002/jlcr.3145

upstream raw materials:

10-(3-(1,3-dioxoisoindolin-2-yl)-2-methylpropyl)-10H-phenothiazine-2-carbonitrile

d6-dimethyl sulfate