Technology Process of 7-CYCLOHEXYL-7-OXOHEPTANOIC ACID
There total 3 articles about 7-CYCLOHEXYL-7-OXOHEPTANOIC ACID which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium methylate; sodium bromide;
In
dichloromethane;
at -5 ℃;
for 1h;
pH=9.2;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: isopropylmagnesium chloride / dichloromethane; tetrahydrofuran / 1 h / -4 - -3 °C
1.2: 2 h / 0 - 20 °C
2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide; sodium hypochlorite; sodium methylate / dichloromethane / 1 h / -5 °C / pH 9.2
With
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; isopropylmagnesium chloride; sodium methylate; sodium bromide;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 168 h / 0 - 25 °C
2.1: isopropylmagnesium chloride / dichloromethane; tetrahydrofuran / 1 h / -4 - -3 °C
2.2: 2 h / 0 - 20 °C
3.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide; sodium hypochlorite; sodium methylate / dichloromethane / 1 h / -5 °C / pH 9.2
With
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; isopropylmagnesium chloride; sodium methylate; 3-chloro-benzenecarboperoxoic acid; sodium bromide;
In
tetrahydrofuran; dichloromethane;
