Methyl 4-fluoro-2-phenylbenzoate

Base Information

Chemical Name:Methyl 4-fluoro-2-phenylbenzoate
CAS No.:724-10-7
Molecular Formula:C₁₄H₁₁FO₂
Molecular Weight:230.239
Hs Code.:
DSSTox Substance ID:DTXSID20709508
Wikidata:Q82644494
Mol file:724-10-7.mol

Synonyms:Methyl 4-fluoro-2-phenylbenzoate;724-10-7;Methyl 5-fluoro-[1,1'-biphenyl]-2-carboxylate;4-fluoro-2-phenyl benzoic acid methyl ester;SCHEMBL6627609;DTXSID20709508;OUVOEZHVKWAICR-UHFFFAOYSA-N;MFCD20231494;AKOS015888671;BS-24406;4-fluoro-2-phenylbenzoic acid methyl ester;CS-0208986;Methyl 5-fluoro[1,1'-biphenyl]-2-carboxylate;Methyl5-fluoro-[1,1'-biphenyl]-2-carboxylate

Suppliers and Price of Methyl 4-fluoro-2-phenylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Methyl4-fluoro-2-phenylbenzoate
1g
$ 557.00

Crysdot
Methyl5-fluoro-[1,1'-biphenyl]-2-carboxylate 95+%
1g
$ 357.00

TRC
Methyl4-fluoro-2-phenylbenzoate
25mg
$ 50.00

Total 5 raw suppliers

Chemical Property of Methyl 4-fluoro-2-phenylbenzoate

Chemical Property:

Boiling Point:108-110 °C(Press: 0.1 Torr)
PSA：26.30000
Density:1.169±0.06 g/cm3(Predicted)
LogP:3.27930
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:230.07430775
Heavy Atom Count:17
Complexity:261

Purity/Quality:

99% ^*data from raw suppliers

Methyl4-fluoro-2-phenylbenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C=C(C=C1)F)C2=CC=CC=C2

Technology Process of Methyl 4-fluoro-2-phenylbenzoate

There total 4 articles about Methyl 4-fluoro-2-phenylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 653-92-9
methyl 2-bromo-4-fluorobenzoate

: 98-80-6
phenylboronic acid

: 724-10-7
4-Fluoro-2-phenyl benzoic acid methyl ester

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; at 80 ℃; Inert atmosphere;
DOI:10.1246/bcsj.20210148

Reference yield:

: 51990-95-5
5-amino-biphenyl-2-carboxylic acid methyl ester

: 724-10-7
4-Fluoro-2-phenyl benzoic acid methyl ester

Guidance literature:: With sodium nitrite; In aqueous HBF₄;

Reference yield:

: 1261678-05-0
methyl 2-iodo-4-fluorobenzoate

: 98-80-6
phenylboronic acid

: 724-10-7
4-Fluoro-2-phenyl benzoic acid methyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In tetrahydrofuran; at 65 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.jafc.9b05751