2-Phenoxypropanamide

Base Information

• Chemical Name: 2-Phenoxypropanamide
• CAS No.: 13532-52-0
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID40405030
• Nikkaji Number: J1.838.084F
• Mol file: 13532-52-0.mol

Synonyms:2-phenoxypropanamide;13532-52-0;Phenetolcarbamid;(S)-2-phenoxy-propanamide;SCHEMBL1328578;DTXSID40405030;AR2180;MFCD01217066;AKOS005246162;SB76470;AS-45289;CS-0217354;EN300-7385653;J-502430

Chemical Property of 2-Phenoxypropanamide

Chemical Property:

• PSA: 53.31000
• LogP: 2.08890
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 165.078978594
• Heavy Atom Count: 12
• Complexity: 153

Purity/Quality:

99% ^*data from raw suppliers

2-Phenoxypropanamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)N)OC1=CC=CC=C1

Technology Process of 2-Phenoxypropanamide

There total 12 articles about 2-Phenoxypropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(2-phenoxypropionylamino)acrylamide (478932-12-6) → 2-phenoxypropionamide (13532-52-0)

Guidance literature:

With hydrogen iodide; methyl iodide; In tetrahydrofuran; at 45 ℃; for 1h; Further Variations:; Reagents; Product distribution;

DOI:10.1021/jo0261698

Reference yield: 83.0%

N-[2-(4-hydroxyphenyl)ethyl]-2-(2-phenoxypropionylamino)acrylamide (478932-13-7) → 2-phenoxypropionamide (13532-52-0)

Guidance literature:

With hydrogen iodide; In tetrahydrofuran; at 45 ℃; for 1h;

DOI:10.1021/jo0261698

Reference yield:

2-phenoxypropanoic acid chloride (122-35-0) → 2-phenoxypropionamide (13532-52-0)

Guidance literature:

With diethyl ether; ammonia;

DOI:10.1021/ja01148a074

upstream raw materials:

ethyl 2-phenoxypropionate

2-phenoxypropanoic acid chloride

sodium phenoxide

2-(2-phenoxypropionylamino)acrylamide

Downstream raw materials:

2-Phenoxy-propionyl isocyanate

2-(1-phenoxy-ethyl)-thiazole

aniline