2-(1-Methyl-1H-pyrrol-2-yl)ethanamine

Base Information

• Chemical Name: 2-(1-Methyl-1H-pyrrol-2-yl)ethanamine
• CAS No.: 83732-75-6
• Molecular Formula: C7H12N2
• Molecular Weight: 124.186
• Hs Code.: 2933990090
• European Community (EC) Number: 280-626-0
• DSSTox Substance ID: DTXSID401003758
• Nikkaji Number: J236.631B
• Wikidata: Q82998432
• Mol file: 83732-75-6.mol

Synonyms:2-(1-Methyl-1H-pyrrol-2-yl)ethanamine;83732-75-6;2-(2-Aminoethyl)-1-methylpyrrole;2-(1-methylpyrrol-2-yl)ethanamine;2-(1-methyl-1H-pyrrol-2-yl)ethan-1-amine;1-Methyl-1H-pyrrole-2-ethylamine;EINECS 280-626-0;2-[2-Aminoethyl]-1-methylpyrrole;1-Methyl-1H-pyrrole-2-ethanamine;ANTIMONY(V)OXIDE;SCHEMBL444647;2-(2-aminoethyl)-1-methylpyrrol;DTXSID401003758;2-(1-Methylpyrrol-2-yl)ethylamine;2-(2-aminoethyl)-1-methyl-pyrrole;MFCD00009753;1H-Pyrrole-2-ethanamine, 1-methyl-;AKOS009287907;SB62721;AS-39382;[2-(1-methyl-1H-pyrrol-2-yl)ethyl]amine;2-(1-Methyl-1H-pyrrol-2-yl)ethanamine #;CS-0117647;FT-0734054;EN300-131971;W-104136;2-(1-Methyl-1H-pyrrol-2-yl)ethanamine, AldrichCPR;F2148-0286

Chemical Property of 2-(1-Methyl-1H-pyrrol-2-yl)ethanamine

Chemical Property:

• Vapor Pressure: 0.083mmHg at 25°C
• Refractive Index: n20/D 1.4684(lit.)
• Boiling Point: 232.1 °C at 760 mmHg
• PKA: 10.40±0.10(Predicted)
• Flash Point: 98.9 °C
• PSA: 30.95000
• Density: 1 g/cm³
• LogP: 1.22660
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 124.100048391
• Heavy Atom Count: 9
• Complexity: 83

Purity/Quality:

97% ^*data from raw suppliers

2-(1-Methyl-1H-pyrrol-2-yl)ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,Xi
• Statements: 22-37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C=CC=C1CCN

Technology Process of 2-(1-Methyl-1H-pyrrol-2-yl)ethanamine

There total 6 articles about 2-(1-Methyl-1H-pyrrol-2-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-methyl-2-pyrroleacetonitrile (24437-41-0) → 2-(2-Aminoethyl)-1-methylpyrrole (83732-75-6)

Guidance literature:

With ammonia; hydrogen; nickel; In ethanol; at 80 ℃; for 8h; under 25857.4 Torr;

DOI:10.1016/S0040-4020(99)00683-3

Reference yield: 81.9%

→ 2-(2-Aminoethyl)-1-methylpyrrole (83732-75-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; water; at 0 - 10 ℃; for 3h; Reflux;

Reference yield: 78.0%

1-methyl-2-(E-2-nitroethenyl)-1H-pyrrole (100446-35-3) → 2-(2-Aminoethyl)-1-methylpyrrole (83732-75-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1002/1521-4184(200107)334:7<241::AID-ARDP241>3.0.CO;2-B

upstream raw materials:

1-methyl-2-pyrroleacetonitrile

1-methyl-2-(2-nitroethenyl)-1H-pyrrole

1-methyl-2-(E-2-nitroethenyl)-1H-pyrrole

N-methylpyrrole aldehyde

Downstream raw materials:

2-(2-hydroxy-ethyl)-N-[2-(1-methyl-1H-pyrrol-2-yl)-ethyl]-benzamide

3-(2-hydroxyethyl)-1H-indole-2-carboxylic acid [2-(1-methyl-1H-pyrrol-2-yl)-ethyl]-amide

2-[2-(p-toluenesulphonylamino)-ethyl]-1-methylpyrrol

2-[2-(p-chlorobenzenesulphonylamino)-ethyl]-1-methylpyrrol