Desisopropyl Zilpaterol Hydrochloride

Base Information

Chemical Name:Desisopropyl Zilpaterol Hydrochloride
CAS No.:92260-83-8
Molecular Formula:C₁₁H₁₃N₃O₂*ClH
Molecular Weight:255.704
Hs Code.:
Mol file:92260-83-8.mol

Synonyms:Desisopropyl Zilpaterol Hydrochloride;trans-6-aMino-4,5,6,7-tetrahydro-7-hydroxy-Midazo[4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

Suppliers and Price of Desisopropyl Zilpaterol Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DesisopropylZilpaterolHydrochloride
25mg
$ 645.00

TRC
DesisopropylZilpaterolHydrochloride
1mg
$ 80.00

American Custom Chemicals Corporation
DESISOPROPYL ZILPATEROL HYDROCHLORIDE 95.00%
50MG
$ 1871.10

American Custom Chemicals Corporation
DESISOPROPYL ZILPATEROL HYDROCHLORIDE 95.00%
5MG
$ 330.00

Total 4 raw suppliers

Chemical Property of Desisopropyl Zilpaterol Hydrochloride

Chemical Property:

Melting Point:250-258°C (dec.)
PSA：84.30000
LogP:2.00860
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

97% ^*data from raw suppliers

DesisopropylZilpaterolHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate to make Zilpaterol.

Technology Process of Desisopropyl Zilpaterol Hydrochloride

There total 2 articles about Desisopropyl Zilpaterol Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1021910-14-4
6-amino-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione hydrochloride

: 1021910-71-3,92260-83-8
6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

Guidance literature:: 6-amino-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione hydrochloride; With sodium tetrahydroborate; In methanol; at 0 - 25 ℃; for 18h;

With hydrogenchloride; In methanol; water;

Reference yield:

1,3-dihydro-1-(1-methylethenyl)-2H-benzimidazol-2-one: 52099-72-6
1,3-dihydro-1-(1-methylethenyl)-2H-benzimidazol-2-one

: 1021910-71-3,92260-83-8
6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

Guidance literature:: Multi-step reaction with 7 steps

1.1: potassium carbonate / acetone / 18 h / Heating / reflux

2.1: sodium hydroxide; water / tetrahydrofuran / 20 °C / Heating / reflux

2.2: 0.5 h / 2 °C

3.1: hydrogenchloride; water / tetrahydrofuran / 2 h

4.1: thionyl chloride / dichloromethane / 2 h / 20 °C

4.2: 20 °C / Heating / reflux

5.1: hydrogenchloride; t-butylnitrite; acetic acid / 1,4-dioxane / 3 h / 20 °C

6.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / methanol / 3 h / 20 °C / 1137.76 Torr

7.1: sodium tetrahydroborate / methanol / 18.5 h / 0 - 20 °C

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; thionyl chloride; t-butylnitrite; water; hydrogen; potassium carbonate; acetic acid; palladium 10% on activated carbon; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; acetone;

Reference yield:

: 1021910-71-3,92260-83-8
6-amino-7-hydroxy-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

: 3-[3-{[(6R,7R)-7-hydroxy-2-oxo-1,2,4,5,6,7-hexahydroimidazo[4,5,1-jk][1]benzazepin-6-yl]amino}butyl]benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / methanol / 1 h

2.1: diethylamine / isopropyl alcohol / Heating / reflux; Sonication

3.1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

4.1: sodium cyanoborohydride; triethylamine / methanol / 18 h / 50 °C

4.2: 0.5 h / 20 °C

With hydrogenchloride; sodium cyanoborohydride; diethylamine; triethylamine; In 1,4-dioxane; methanol; isopropyl alcohol;