trans-Capsaicin-d3

Base Information

Chemical Name:trans-Capsaicin-d3
CAS No.:1217899-52-9
Molecular Formula:C18H27NO3
Molecular Weight:308.393
Hs Code.:
Mol file:1217899-52-9.mol

Synonyms:trans-Capsaicin-d3

Suppliers and Price of trans-Capsaicin-d3

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of trans-Capsaicin-d3

Chemical Property:

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-Capsaicin-d3

There total 6 articles about trans-Capsaicin-d3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 59320-77-3
trans-8-methyl-6-nonenoic acid

: 1217899-51-8
4-(aminomethyl)-2-methoxy-d3-phenol hydrochloride

: 1217899-52-9
(E)-N-(4-hydroxy-3-methoxy-d3-benzyl)-8-methylnon-6-enamide

Guidance literature:: trans-8-methyl-6-nonenoic acid; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.25h;

4-(aminomethyl)-2-methoxy-d3-phenol hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

Reference yield:

: 1217899-51-8
4-(aminomethyl)-2-methoxy-d3-phenol hydrochloride

: 95636-02-5
(E)-8-Methylnon-6-enoic acid chloride

: 1217899-52-9
(E)-N-(4-hydroxy-3-methoxy-d3-benzyl)-8-methylnon-6-enamide

Guidance literature:: 4-(aminomethyl)-2-methoxy-d3-phenol hydrochloride; With sodium hydroxide; In water;

(E)-8-Methylnon-6-enoic acid chloride; In tetrahydrofuran; at 20 ℃; Reflux;
DOI:10.1002/jlcr.1678

Reference yield:

: 139-85-5
3,4-dihydroxybenzaldehyde

: 1217899-52-9
(E)-N-(4-hydroxy-3-methoxy-d3-benzyl)-8-methylnon-6-enamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / acetonitrile / 0.08 h

1.2: 6 h / 60 °C

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0.08 h / 0 °C

2.2: 1 h / 20 °C

3.1: hydroxylamine hydrochloride; sodium acetate / acetonitrile; water / 2 h / Reflux

4.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / water; ethanol / 3 h / 20 °C / 1551.49 Torr

5.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.25 h / 0 - 20 °C

5.2: 2 h / 0 - 20 °C

With hydrogenchloride; di-isopropyl azodicarboxylate; palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen; sodium acetate; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; acetonitrile;