3-BROMO-4-(4-CYANOPHENYL)-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE

Base Information

• Chemical Name: 3-BROMO-4-(4-CYANOPHENYL)-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE
• CAS No.: 950985-29-2
• Molecular Formula: C17H11BrN2O
• Molecular Weight: 339.19
• Hs Code.: 2933499090
• Mol file: 950985-29-2.mol

Synonyms:3-BROMO-4-(4-CYANOPHENYL)-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE

Chemical Property of 3-BROMO-4-(4-CYANOPHENYL)-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE

Chemical Property:

• PSA: 45.79000
• LogP: 3.83968

Purity/Quality:

98%Min ^*data from raw suppliers

3-Bromo-4-(4-cyanophenyl)-1-methyl-2-oxo-1,2-dihydroquinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BROMO-4-(4-CYANOPHENYL)-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE

There total 1 articles about 3-BROMO-4-(4-CYANOPHENYL)-1-METHYL-2-OXO-1,2-DIHYDROQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-bromo-4-trifloxy-quinolin-2(1H)-one (853192-53-7) + 4-cyanophenylboronic acid (126747-14-6) → 4-(3-bromo-1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)-benzonitrile (950985-29-2)

Guidance literature:

With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1016/j.tet.2007.12.003

Reference yield:

4-(3-bromo-1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)-benzonitrile (950985-29-2) + 2-[(trimethylsilyl)ethynyl]aniline (103529-16-4) → C25H17N3O

Guidance literature:

With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 50 ℃;

DOI:10.1016/j.tet.2007.12.003

upstream raw materials:

3-bromo-4-trifloxy-quinolin-2(1H)-one

4-cyanophenylboronic acid