4,7-Dibromo-1H-indole-2,3-dione

Base Information

Chemical Name:4,7-Dibromo-1H-indole-2,3-dione
CAS No.:20780-89-6
Molecular Formula:C8H3Br2NO2
Molecular Weight:304.925
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90475965
Nikkaji Number:J16.799A
Wikidata:Q82306806
Mol file:20780-89-6.mol

Synonyms:20780-89-6;4,7-Dibromo-1H-indole-2,3-dione;4,7-dibromo-2,3-dihydro-1H-indole-2,3-dione;SCHEMBL17265675;DTXSID90475965;AKOS010727871;AT33918;4,7-DIBROMOINDOLINE-2,3-DIONE;CS-0261203;EN300-77631;Z819227448

Suppliers and Price of 4,7-Dibromo-1H-indole-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4,7-Dibromo-1H-indole-2,3-dione

Chemical Property:

PKA:7.65±0.20(Predicted)
PSA：46.17000
Density:2.179±0.06 g/cm3(Predicted)
LogP:2.48440
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:304.85100
Heavy Atom Count:13
Complexity:269

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C2C(=C1Br)C(=O)C(=O)N2)Br
Uses 4,7-Dibromo-2,3-dihydro-1H-indole-2,3-dione is used in conjugated thiophene-Fused Isatin dyes through intramolecular direct arylation.

Technology Process of 4,7-Dibromo-1H-indole-2,3-dione

There total 2 articles about 4,7-Dibromo-1H-indole-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 529502-68-9
N-(2,5-dibromophenyl)-2-(N-hydroxyimino)acetamide

: 20780-89-6
4,7-dibromo-2,3-dihydro-1H-indole-2,3-dione

Guidance literature:: With sulfuric acid; at 100 ℃;
DOI:10.1021/jacs.7b00776

Reference yield:

: 3638-73-1
2,5-dibromoaniline

: 20780-89-6
4,7-dibromo-2,3-dihydro-1H-indole-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 13.5 g / hydroxylamine hydrochloride; aq. Na₂SO₄ / ethanol / 12 h / Heating

2: 47 percent / aq. H₂SO₄ / 0.25 h / 100 °C

With sulfuric acid; hydroxylamine hydrochloride; sodium sulfate; In ethanol;