Acetyl Tetrapeptide-3

Base Information

• Chemical Name: Acetyl Tetrapeptide-3
• CAS No.: 827306-88-7
• Molecular Formula: C22H39N9O5
• Molecular Weight: 509.6
• UNII: D1HW9N9QBX
• RXCUI: 2000919
• Wikidata: Q27275970
• Mol file: 827306-88-7.mol

Synonyms:Acetyl Tetrapeptide-3;827306-88-7;Folixyl;Kollaren 6;Acetyl tetrapeptide-1;Uxi hair growth peptide;Ac-lys-gly-his-lys-NH2;D1HW9N9QBX;Acetyl tetrapeptide-3 [INCI];N2-Acetyl-L-lysylglycyl-L-histidyl-L-lysinamide;L-Lysinamide, N2-acetyl-L-lysylglycyl-L-histidyl-;(S)-2-acetamido-6-amino-N-(2-(((S)-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)hexanamide;AcetylTetrapeptide-3;UNII-D1HW9N9QBX;HY-W129161;(2S)-2-[[(2S)-2-[[2-[[(2S)-2-acetamido-6-aminohexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanamide;AS-84275;CS-0187299;D83845;A915562;Q27275970

Chemical Property of Acetyl Tetrapeptide-3

Chemical Property:

• Boiling Point: 1075.4±65.0 °C(Predicted)
• PKA: 13.35±0.46(Predicted)
• PSA: 240.21000
• Density: 1.250±0.06 g/cm3(Predicted)
• LogP: 0.95050
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility.: DMF: 14 mg/ml DMSO: 10 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 10 mg/ml
• XLogP3: -3
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 18
• Exact Mass: 509.30741538
• Heavy Atom Count: 36
• Complexity: 737

Purity/Quality:

99% ^*data from raw suppliers

Acetyltetrapeptide-3 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)NC(CCCCN)C(=O)NCC(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)N
• Isomeric SMILES: CC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)N
• Description: Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.
• Uses: Acetyl tetrapeptide-3 stimulates hair growth with higher activity than the reference hair growth product, Minoxidil. This can help to anchor the hair fibre into the scalp which can strengthen strands and target the causes of hair loss. By combining this ingredient with Red Clover Extract, the benefits can be accelerated helping to improve blood circulation to the roots, increasing thickness and hair volume.
• Biological Functions: Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.

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