Technology Process of 6-(trifluoroMethyl)quinoline-4-carbaldehyde
There total 2 articles about 6-(trifluoroMethyl)quinoline-4-carbaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dichloro-acetic acid; [bis(acetoxy)iodo]benzene; water;
In
dimethyl sulfoxide;
at 20 ℃;
for 48h;
chemoselective reaction;
Sealed tube;
DOI:10.1002/asia.202100704
- Guidance literature:
-
Multi-step reaction with 2 steps
1: manganese(ll) chloride / tetrahydrofuran / 3 h / 0 °C / Inert atmosphere
2: [bis(acetoxy)iodo]benzene; dichloro-acetic acid; water / dimethyl sulfoxide / 48 h / 20 °C / Sealed tube
With
dichloro-acetic acid; [bis(acetoxy)iodo]benzene; water; manganese(ll) chloride;
In
tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1002/asia.202100704