5-Oxo-2-prop-2-en-1-ylproline

Base Information

Chemical Name:5-Oxo-2-prop-2-en-1-ylproline
CAS No.:406478-96-4
Molecular Formula:C8H11NO3
Molecular Weight:169.18
Hs Code.:
DSSTox Substance ID:DTXSID60697738
Mol file:406478-96-4.mol

Synonyms:5-Oxo-2-prop-2-en-1-ylproline;406478-96-4;5-oxo-2-prop-2-enylpyrrolidine-2-carboxylic acid;SCHEMBL21645421;DTXSID60697738

Suppliers and Price of 5-Oxo-2-prop-2-en-1-ylproline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-2-(2-PROPENYL)-2-CARBOXY-5-OXO-PYRROLIDINE 95.00%
5MG
$ 498.23

AccelPharmtech
5-oxo-2-(2-propen-1-yl)-L-Proline 97.00%
5G
$ 2330.00

Total 3 raw suppliers

Chemical Property of 5-Oxo-2-prop-2-en-1-ylproline

Chemical Property:

PSA：66.40000
LogP:0.62470
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:169.07389321
Heavy Atom Count:12
Complexity:237

Purity/Quality:

98% ^*data from raw suppliers

(S)-2-(2-PROPENYL)-2-CARBOXY-5-OXO-PYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CCC1(CCC(=O)N1)C(=O)O

Technology Process of 5-Oxo-2-prop-2-en-1-ylproline

There total 5 articles about 5-Oxo-2-prop-2-en-1-ylproline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: (2R)-2-(prop-2-enyl)-5-oxoproline (1S,2R,5S)-5-methyl-2-(1-methylethyl)cyclohexyl ester

: 406478-96-4
(R)-2-allyl-5-oxopyrrolidine-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; at 25 ℃; for 18h;
DOI:10.1016/S0968-0896(01)00287-5

Reference yield: 77.0%

: 4931-79-7
(S)-allyl 5-oxopyrrolidine-2-carboxylate

: 406478-96-4
(R)-2-allyl-5-oxopyrrolidine-2-carboxylic acid

Guidance literature:: With aluminum isopropoxide; lithium hexamethyldisilazane; Quinine; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1039/b811642c

Reference yield:

: 868066-06-2
ethyl 2-allyl-5-oxopyrrolidine-2-carboxylate

: (S)-2-allyl-5-oxopyrrolidine-2-carboxylic acid

: 406478-96-4
(R)-2-allyl-5-oxopyrrolidine-2-carboxylic acid

Guidance literature:: ethyl 2-allyl-5-oxopyrrolidine-2-carboxylate; With water; potassium hydroxide; In methanol; at 20 ℃; for 2h; Inert atmosphere;

With N-ethyl-N,N-diisopropylamine; In methanol; Resolution of racemate; Supercritical conditions;