N-(4-Methylbenzyl)cyclopentanamine hydrochloride

Base Information

• Chemical Name: N-(4-Methylbenzyl)cyclopentanamine hydrochloride
• CAS No.: 70000-57-6
• Molecular Formula: C13H19N
• Molecular Weight: 189.3
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID00589486
• Mol file: 70000-57-6.mol

Synonyms:N-(4-METHYLBENZYL)CYCLOPENTANAMINE HYDROCHLORIDE;1158414-41-5;N-[(4-methylphenyl)methyl]cyclopentanamine hydrochloride;N-[(4-methylphenyl)methyl]cyclopentanamine;hydrochloride;DTXSID00589486;MFCD07105721;AKOS015888757;N-(4-Methylbenzyl)cyclopentanamine HCl;BS-39653;N-(4-METHYLBENZYL)CYCLOPENTANAMINEHYDROCHLORIDE;N-(4-Methylbenzyl)cyclopentanamine hydrochloride;95%;N-[(4-Methylphenyl)methyl]cyclopentanamine--hydrogen chloride (1/1)

Chemical Property of N-(4-Methylbenzyl)cyclopentanamine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0021mmHg at 25°C
• Boiling Point: 290.2°C at 760 mmHg
• Flash Point: 130.9°C
• PSA: 12.03000
• Density: 0.97g/cm³
• LogP: 4.22010
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 225.1284273
• Heavy Atom Count: 15
• Complexity: 153

Purity/Quality:

98%Min ^*data from raw suppliers

N-(4-methylbenzyl)cyclopentanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)CNC2CCCC2.Cl

Technology Process of N-(4-Methylbenzyl)cyclopentanamine hydrochloride

There total 5 articles about N-(4-Methylbenzyl)cyclopentanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

N-(benzenesulfenyl)-N-(p-methylbenzyl)cyclopentylamine (138710-08-4) → N-(p-methylbenzyl)cyclopentylamine (70000-57-6)

Guidance literature:

With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile); In cyclohexane; for 1.5h; Heating;

DOI:10.1016/0040-4039(91)80190-H

Reference yield:

N-(4-methylbenzylidene)cyclopentanamine (946495-11-0) → N-(p-methylbenzyl)cyclopentylamine (70000-57-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; Yield given; Heating;

DOI:10.1016/S0040-4020(01)80837-1

Reference yield:

Cyclopentamine (1003-03-8) → N-(p-methylbenzyl)cyclopentylamine (70000-57-6)

Guidance literature:

Multi-step reaction with 2 steps

1: p-TsOH / toluene / Heating

2: NaBH₄ / methanol / Heating

With sodium tetrahydroborate; toluene-4-sulfonic acid; In methanol; toluene;

DOI:10.1016/S0040-4020(01)80837-1

upstream raw materials:

N-(benzenesulfenyl)-N-(p-methylbenzyl)cyclopentylamine

N-(4-methylbenzylidene)cyclopentanamine

4-methyl-benzaldehyde

Cyclopentamine

Downstream raw materials:

N-(benzenesulfenyl)-N-(p-methylbenzyl)cyclopentylamine