Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate

Base Information

Chemical Name:Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate
CAS No.:636559-71-2
Molecular Formula:C28H30O5S
Molecular Weight:478.609
Hs Code.:

Synonyms:Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate

Suppliers and Price of Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate

There total 11 articles about Phenyl 6-deoxy-3,4-bis-O-(phenylmethyl)-1-thio-alpha-L-mannopyranoside acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 108-24-7
acetic anhydride

: 172296-66-1
Phenyl 3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

: 636559-71-2
phenyl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

Guidance literature:: With magnesium triflate; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.joc.7b00561

Reference yield:

: 1214-98-8,105026-40-2,127061-11-4,131724-82-8
phenyl 1-thio-α-L-rhamnopyranose

: 636559-71-2
phenyl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: camphor-10-sulfonic acid / acetone / 1 h / 20 °C

2.1: acetic acid / water / 3 h / 90 °C

3.1: di(n-butyl)tin oxide; benzene / 5 h / Reflux

3.2: 2 h / 20 °C

4.1: pyridine / 1 h / 0 - 20 °C / Inert atmosphere

With pyridine; camphor-10-sulfonic acid; di(n-butyl)tin oxide; acetic acid; benzene; In water; acetone;
DOI:10.1016/j.carres.2014.11.005

Reference yield:

: 73-34-7
L-rhamnose

: 636559-71-2
phenyl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 9 steps

1: triethylamine / dmap / dichloromethane / 16 h / 20 °C

2: tin(IV) chloride / dichloromethane / 5 h / 0 °C

3: potassium carbonate / tetrahydrofuran; methanol / 16 h / 20 °C

4: toluene-4-sulfonic acid

5: sodium hydride / DMF (N,N-dimethyl-formamide)

6: trifluoroacetic acid / methanol / 16 h / 50 °C

7: toluene / 4 h / Heating / reflux

8: tetrabutylammomium bromide / 5 h / 50 °C

9: pyridine

With pyridine; tetrabutylammomium bromide; tin(IV) chloride; sodium hydride; triethylamine; trifluoroacetic acid; dmap; potassium carbonate; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; DMF (N,N-dimethyl-formamide); dichloromethane; toluene;