Strobilurin G

Base Information

Chemical Name:Strobilurin G
CAS No.:132056-04-3
Molecular Formula:C₂₆H₃₄O₆
Molecular Weight:442.552
Hs Code.:
UNII:49G3784VEO
ChEMBL ID:CHEMBL4636674

Synonyms:3,5-hexadienoic acid, 6-((3S)-3,4-dihydro-4,4-dimethyl-3-((3-methyl-2-butenyl)oxy)-2h-1,5-benzodioxepin-7-yl)-2-(methoxymethylene)-3-methyl-, methyl ester, (2E,3Z,5E)-;strobilurin D;strobilurin G

Suppliers and Price of Strobilurin G

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Strobilurin G

Chemical Property:

Vapor Pressure:1.84E-13mmHg at 25°C
Boiling Point:580.3°Cat760mmHg
Flash Point:246.9°C
PSA：66.52000
Density:1.082g/cm³
LogP:5.25060
XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:442.23553880
Heavy Atom Count:32
Complexity:741

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CCOC1COC2=C(C=C(C=C2)C=CC=C(C)C(=COC)C(=O)OC)OC1(C)C)C
Isomeric SMILES:CC(=CCO[C@H]1COC2=C(C=C(C=C2)/C=C/C=C(/C)\C(=C/OC)\C(=O)OC)OC1(C)C)C

Technology Process of Strobilurin G

There total 7 articles about Strobilurin G which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: methyl (Z)-2-tributylstannyl-3-methoxypropenoate

: 716305-20-3
(S)-(1E,3Z)-8-(4-iodopenta-1,3-dienyl)-2,2-dimethyl-3-(3-methyl-2-butenyloxy)-3,4-dihydro-2H-benzo[b][1,4]dioxepin

: 132056-04-3,129145-64-8
strobilurin G

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1-methyl-pyrrolidin-2-one; at 50 ℃; for 24h;
DOI:10.1016/j.tet.2004.03.092

Reference yield:

: 870-63-3
prenyl bromide

: 132056-04-3,129145-64-8
strobilurin G

Guidance literature:: Multi-step reaction with 6 steps

1.1: 92 percent / NaH / dimethylformamide / 16 h / 0 °C

2.1: 87 percent / DIBAL-H / tetrahydrofuran / 2 h / -78 °C

3.1: 80 percent / MnO₂ / CH₂Cl₂ / 48 h / 20 °C

4.1: n-BuLi / tetrahydrofuran / 1 h / -40 °C

4.2: 40 percent / tetrahydrofuran / 2 h / 20 °C

5.1: 63 percent / KI; HMPT; CuI / 48 h / 120 °C

6.1: 38 percent / Pd(PPh₃)4; CuI / 1-methyl-pyrrolidin-2-one / 24 h / 50 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; manganese(IV) oxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium hydride; diisobutylaluminium hydride; potassium iodide; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane; N,N-dimethyl-formamide; 4.2: Wittig reaction / 6.1: Stille cross-coupling reaction;
DOI:10.1016/j.tet.2004.03.092

Reference yield:

: 247922-50-5
ethyl (S)-3-(3-hydroxy-4,4-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)acrylate

: 132056-04-3,129145-64-8
strobilurin G

Guidance literature:: Multi-step reaction with 6 steps

1.1: 92 percent / NaH / dimethylformamide / 16 h / 0 °C

2.1: 87 percent / DIBAL-H / tetrahydrofuran / 2 h / -78 °C

3.1: 80 percent / MnO₂ / CH₂Cl₂ / 48 h / 20 °C

4.1: n-BuLi / tetrahydrofuran / 1 h / -40 °C

4.2: 40 percent / tetrahydrofuran / 2 h / 20 °C

5.1: 63 percent / KI; HMPT; CuI / 48 h / 120 °C

6.1: 38 percent / Pd(PPh₃)4; CuI / 1-methyl-pyrrolidin-2-one / 24 h / 50 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; manganese(IV) oxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium hydride; diisobutylaluminium hydride; potassium iodide; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane; N,N-dimethyl-formamide; 4.2: Wittig reaction / 6.1: Stille cross-coupling reaction;
DOI:10.1016/j.tet.2004.03.092