7-(Bromomethyl)-1-chloro-6-methoxyisoquinoline

Base Information

Chemical Name:7-(Bromomethyl)-1-chloro-6-methoxyisoquinoline
CAS No.:209286-02-2
Molecular Formula:C₁₁H₉BrClNO
Molecular Weight:286.556
Hs Code.:
DSSTox Substance ID:DTXSID00592576
Wikidata:Q82486760
Mol file:209286-02-2.mol

Synonyms:7-(BROMOMETHYL)-1-CHLORO-6-METHOXYISOQUINOLINE;209286-02-2;7-bromomethyl-1-chloro-6-methoxy-isoquinoline;SCHEMBL7220135;DTXSID00592576;CVXKQBFZIPGZIE-UHFFFAOYSA-N;AB63904;DB-207857

Suppliers and Price of 7-(Bromomethyl)-1-chloro-6-methoxyisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-(Bromomethyl)-1-chloro-6-methoxyisoquinoline

Chemical Property:

PSA：22.12000
LogP:3.79170
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:284.95560
Heavy Atom Count:15
Complexity:217

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)C=CN=C2Cl)CBr

Technology Process of 7-(Bromomethyl)-1-chloro-6-methoxyisoquinoline

There total 2 articles about 7-(Bromomethyl)-1-chloro-6-methoxyisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 209286-03-3
1-chloro-6-methoxy-7-methyl-isoquinoline

: 209286-02-2
7-bromomethyl-1-chloro-6-methoxy-isoquinoline

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; Heating;
DOI:10.1016/S0960-894X(99)00421-7

Reference yield:

: 209286-01-1
6-Methoxy-7-methyl-2H-isoquinolin-1-one

: 209286-02-2
7-bromomethyl-1-chloro-6-methoxy-isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / Heating

2: NBS; (PhCO₂)2 / CCl₄ / Heating

With N-Bromosuccinimide; trichlorophosphate; dibenzoyl peroxide; In tetrachloromethane; 1: Chlorination / 2: Bromination;
DOI:10.1016/S0960-894X(99)00421-7