1-(o-Methoxybenzyl)-1H-benzotriazole

Base Information

• Chemical Name: 1-(o-Methoxybenzyl)-1H-benzotriazole
• CAS No.: 27799-80-0
• Molecular Formula: C14H13N3O
• Molecular Weight: 239.27
• Hs Code.: 2933990090
• Mol file: 27799-80-0.mol

Synonyms:1-(o-Methoxybenzyl)-1H-benzotriazole

Chemical Property of 1-(o-Methoxybenzyl)-1H-benzotriazole

Chemical Property:

• PSA: 39.94000
• LogP: 2.48820

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(o-Methoxybenzyl)-1H-benzotriazole

There total 4 articles about 1-(o-Methoxybenzyl)-1H-benzotriazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

C20H16N6O (1421826-44-9) → 3-(2-methoxyphenyl)benzo[e][1,2,4]triazine (1071693-25-8) + 1-(2-methoxybenzyl)-1H-benzo[d][1,2,3]triazole (27799-80-0)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; allylsamarium bromide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/cjoc.201200989

Reference yield:

1,2,3-Benzotriazole (95-14-7,27556-51-0) + (2-methoxyphenyl)methanol (612-16-8) → C14H13N3O (1339958-74-5) + 1-(2-methoxybenzyl)-1H-benzo[d][1,2,3]triazole (27799-80-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 3h; regioselective reaction; Inert atmosphere; Cooling with ice;

DOI:10.1002/asia.201100357

Reference yield:

ortho-anisaldehyde (135-02-4) → 1-(2-methoxybenzyl)-1H-benzo[d][1,2,3]triazole (27799-80-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,4-dioxane / 2 h / 60 °C

2: copper; potassium tert-butylate / dimethyl sulfoxide / 6 h / 60 °C

With potassium tert-butylate; copper; In 1,4-dioxane; dimethyl sulfoxide;

DOI:10.1002/jhet.1616

upstream raw materials:

1,2,3-Benzotriazole

(2-methoxyphenyl)methanol

C₂₀H₁₆N₆O

2-methoxybenzaldehyde p-toluenesulfonylhydrazone