Chemical Property of Levomilnacipran hydrochloride
Chemical Property:
- PSA：46.33000
- LogP:3.27370
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:5
- Exact Mass:282.1498911
- Heavy Atom Count:19
- Complexity:295
- Purity/Quality:
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99%, *data from raw suppliers
(1S-cis)-MilnacipranHydrochloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
- Canonical SMILES:CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2.Cl
- Isomeric SMILES:CCN(CC)C(=O)[C@]1(C[C@H]1CN)C2=CC=CC=C2.Cl
- Recent ClinicalTrials:Effect of F2695 on Brain Activity Measured by Functional Magnetic Resonance Imaging
- Recent EU Clinical Trials:A European Phase III, Multicentre, Double-blind, Randomised, Placebo-Controlled Monotherapy Study of Milnacipran for the Treatment of the Fibromyalgia Syndrome.
- Recent NIPH Clinical Trials:None
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Description
Levomilnacipran (Fetzima?) is a dual serotonin–norepinephrine
reuptake inhibitor (SNRI) approved by the FDA in 2013 for the
treatment of major depressive disorders (MDD).
Levomilnacipran is the most active enantiomer of the racemate
Milnacipran, which is currently used to treat pain associated
with fibromyalgia. The drug was developed by Forest
Laboratories and the Pierre Fabre group.
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Uses
The S-enatiomer of Milnacipran (M344600). The (1S-cis)-enatiomer of Milnacipran (M344600). The (1S-cis)-enatiomer of Milnacipran (M344600). A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
