6-Methoxy-2-pyridineacetic acid

Base Information

• Chemical Name: 6-Methoxy-2-pyridineacetic acid
• CAS No.: 944896-97-3
• Molecular Formula: C8H9NO3
• Molecular Weight: 167.164
• Mol file: 944896-97-3.mol

Synonyms:6-Methoxy-2-pyridineacetic acid;2-(6-Methoxy-2-pyridyl)acetic Acid

Chemical Property of 6-Methoxy-2-pyridineacetic acid

Chemical Property:

• Vapor Pressure: 0.000734mmHg at 25°C
• Boiling Point: 294.5°C at 760 mmHg
• PKA: 4.14±0.12(Predicted)
• Flash Point: 131.9°C
• PSA: 59.42000
• Density: 1.246g/cm³
• LogP: 0.71730
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(6-Methoxy-pyridin-2-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Methoxy-2-pyridineacetic acid

There total 1 articles about 6-Methoxy-2-pyridineacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

[(6-MeO-C5H3N-2-CH2CO)Fe(CO)2(CH3CN)2](BF4) (1376766-14-1) → 2-(6-methoxypyridin-2-yl)acetic acid (944896-97-3)

Guidance literature:

In water; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/chem.201201954

Reference yield: 75.0%

2-(6-methoxypyridin-2-yl)acetic acid (944896-97-3) + 1,2-diamino-3-(bis(4-methoxybenzyl)amino)-5-bromopyrazin-1-ium 2,4,6- trimethylbenzenesulfonate → 6-bromo-N,N-bis(4-methoxybenzyl)-2-((6-methoxypyridin-2-yl)methyl)-[1,2,4]triazolo[1,5-a]pyrazin-8-amine

Guidance literature:

With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 20 ℃; for 6h;

upstream raw materials:

[(6-MeO-C₅H₃N-2-CH₂CO)Fe(CO)2(CH₃CN)2](BF₄)