2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine

Base Information

Chemical Name:2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine
CAS No.:122479-08-7
Molecular Formula:C₂₁H₂₁N₅O₂
Molecular Weight:375.43
Hs Code.:
UNII:VW8QLT5H8X
ChEMBL ID:CHEMBL1339029
DSSTox Substance ID:DTXSID301028519
Nikkaji Number:J493.098C
Wikidata:Q5512946
Wikipedia:GBLD-345
Mol file:122479-08-7.mol

Synonyms:GBLD 345;122479-08-7;GBLD345;GBLD-345;2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine;2-(4-AMINOPHENYL)-3-METHOXY-6-(3-METHOXYPHENYL)-METHYLIMIDAZO[1,2-B]PYRIDAZINE;2-(4-Aminophenyl)-3-methoxy-N-((3-methoxyphenyl)methyl)imidazo(1,2-b)pyridazin-6-amine;NCGC00024779-01;Tocris-0770;VW8QLT5H8X;Biomol-NT_000281;BPBio1_001364;CHEMBL1339029;SCHEMBL12648675;DTXSID301028519;NCGC00024779-02;HY-103535;CS-0028035;SR-01000597704;Q5512946;SR-01000597704-1;2-(4-Aminophenyl)-3-methoxy-N-(3-methoxybenzyl)imidazo[1,2-b]pyridazin-6-amine;Imidazo[1,2-b]pyridazin-6-amine, 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]-

Suppliers and Price of 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
GBLD-345 95.00%
10MG
$ 697.34

Total 8 raw suppliers

Chemical Property of 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine

Chemical Property:

PSA：86.70000
LogP:4.26200
Storage Temp.:Store at RT
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:375.16952493
Heavy Atom Count:28
Complexity:487

Purity/Quality:

98%Min ^*data from raw suppliers

GBLD-345 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)CNC2=NN3C(=NC(=C3OC)C4=CC=C(C=C4)N)C=C2

Technology Process of 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine

There total 5 articles about 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]imidazo[1,2-b]pyridazin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122479-07-6
3-methoxy-6-(3'-methoxybenzylamino)-2-(4''-nitrophenyl)imidazo<1,2-b>pyridazine

: 122479-08-7
2-(4'-aminophenyl)-3-methoxy-6-(3''-methoxybenzylamino)imidazo<1,2-b>pyridazine

Guidance literature:: With hydrogenchloride; iron; In methanol; water; at 85 - 90 ℃; for 3h;

Reference yield:

: 5071-96-5
3-METHOXYBENZYLAMINE

: 122479-08-7
2-(4'-aminophenyl)-3-methoxy-6-(3''-methoxybenzylamino)imidazo<1,2-b>pyridazine

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / 20 h / 160 °C

2: ethanol / 0.5 h / Heating

3: diethyl ether / 20 °C

4: 0.02 g / iron, HCl / methanol; H₂O / 3 h / 85 - 90 °C

With hydrogenchloride; iron; In methanol; diethyl ether; ethanol; water;

Reference yield:

: 99-81-0
4-Nitrophenacyl bromide

: 122479-08-7
2-(4'-aminophenyl)-3-methoxy-6-(3''-methoxybenzylamino)imidazo<1,2-b>pyridazine

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 0.5 h / Heating

2: diethyl ether / 20 °C

3: 0.02 g / iron, HCl / methanol; H₂O / 3 h / 85 - 90 °C

With hydrogenchloride; iron; In methanol; diethyl ether; ethanol; water;