2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HCL

Base Information

• Chemical Name: 2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HCL
• CAS No.: 497853-85-7
• Molecular Formula: C9H16Cl2N2
• Molecular Weight: 223.145
• Mol file: 497853-85-7.mol

Synonyms:2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HCL

Chemical Property of 2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HCL

Chemical Property:

• PSA: 17.82000
• LogP: 3.61410

Purity/Quality:

2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HCL

There total 1 articles about 2-CHLOROMETHYL-1-PENTYLIMIDAZOLE HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxymethyl-1-pentylimidazole (497855-81-9) → 2-chloromethyl-1-pentylimidazole hydrochloride (497853-85-7)

Guidance literature:

With thionyl chloride; at 0 - 90 ℃; for 0.5h;

Reference yield:

2-chloromethyl-1-pentylimidazole hydrochloride (497853-85-7) + S-<(benzyloxy)carbonyl>-4-aminobenzenethiol (130219-46-4) + 7-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid (313736-34-4) → 7-[4-(2-butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[(1-pentylimidazol-2-yl)methyl]sulfanyl]phenyl]-2,3-dihydro-1-benzazepine-4-carboxamide

Guidance literature:

7-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid; With thionyl chloride; N,N-dimethyl-formamide; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

S-<(benzyloxy)carbonyl>-4-aminobenzenethiol; With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

2-chloromethyl-1-pentylimidazole hydrochloride; With sodium hydroxide; more than 3 stages;

upstream raw materials:

2-hydroxymethyl-1-pentylimidazole

Refernces