1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine

Base Information

Chemical Name:1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine
CAS No.:116818-82-7
Molecular Formula:C₁₀H₁₉N₃O
Molecular Weight:197.28
Hs Code.:2933990090
European Community (EC) Number:675-497-6
Mol file:116818-82-7.mol

Synonyms:116818-82-7;1-methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine;(4-Methyl-piperazin-1-yl)-pyrrolidin-2-yl-methanone;1-methyl-4-(pyrrolidine-2-carbonyl)piperazine;(4-methylpiperazin-1-yl)-pyrrolidin-2-ylmethanone;(4-Methylpiperazin-1-yl)(pyrrolidin-2-yl)methanone;SCHEMBL3331942;FXYNRDLXGBFSTB-UHFFFAOYSA-N;AKOS000164716;AKOS024152339;SB46945;2-(4-methylpiperazin-1-ylcarbonyl)pyrrolidine;EN300-37503;1-methyl-4-(2-pyrrolidinylcarbonyl)-piperazine;G56969;J-000056;Methanone, (4-methyl-1-piperazinyl)-2-pyrrolidinyl-;Z241832786;(4-methyl-piperazin-1-yl)-pyrrolidin-2-yl-methanone, AldrichCPR

Suppliers and Price of 1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(4-Methylpiperazin-1-yl)(pyrrolidin-2-yl)methanone 97%
1g
$ 583.00

American Custom Chemicals Corporation
1-METHYL-4-(PYRROLIDIN-2-YLCARBONYL)PIPERAZINE 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
1-METHYL-4-(PYRROLIDIN-2-YLCARBONYL)PIPERAZINE 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
1-METHYL-4-(PYRROLIDIN-2-YLCARBONYL)PIPERAZINE 95.00%
1G
$ 983.52

AK Scientific
1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine
250mg
$ 340.00

Total 4 raw suppliers

Chemical Property of 1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine

Chemical Property:

PSA：35.58000
LogP:-0.28300
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:197.152812238
Heavy Atom Count:14
Complexity:211

Purity/Quality:

97% ^*data from raw suppliers

(4-Methylpiperazin-1-yl)(pyrrolidin-2-yl)methanone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C(=O)C2CCCN2

Technology Process of 1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine

There total 5 articles about 1-Methyl-4-(pyrrolidin-2-ylcarbonyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 100158-67-6
(S)-4-methyl-1-piperazine

: 100158-68-7,116818-82-7
(4-Methyl-piperazin-1-yl)-(S)-pyrrolidin-2-yl-methanone

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield:

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: N-methylpiperazin hydrochloride

: 100158-68-7,116818-82-7
(4-Methyl-piperazin-1-yl)-(S)-pyrrolidin-2-yl-methanone

Guidance literature:: 1-(tert-butoxycarbonyl)-L-proline; With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In dichloromethane; at 5 ℃; for 16h;

N-methylpiperazin hydrochloride; With triethylamine; at 20 ℃; for 48h;

With hydrogenchloride; In water; at 20 ℃; for 3h;