5-Hydroxy-3'-methoxyflavone

Base Information

Chemical Name:5-Hydroxy-3'-methoxyflavone
CAS No.:6697-60-5
Molecular Formula:C16H12O4
Molecular Weight:268.269
Hs Code.:
DSSTox Substance ID:DTXSID101346911
Wikidata:Q63408917
Metabolomics Workbench ID:74596
Mol file:6697-60-5.mol

Synonyms:5-HYDROXY-3'-METHOXYFLAVONE;6697-60-5;SCHEMBL4650052;IPQOBEBHJDIMQR-UHFFFAOYSA-N;DTXSID101346911;AKOS024285400;5-hydroxy-3'-methoxyflavone, AldrichCPR;Q63408917;4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-methoxyphenyl)-

Suppliers and Price of 5-Hydroxy-3'-methoxyflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-Hydroxy-3'-methoxyflavone

Chemical Property:

Melting Point:145-148 °C(Solv: ethanol (64-17-5))
Boiling Point:465.0±45.0 °C(Predicted)
PKA:6.77±0.40(Predicted)
PSA：59.67000
Density:1.329±0.06 g/cm3(Predicted)
LogP:3.17420
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:268.07355886
Heavy Atom Count:20
Complexity:403

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=CC(=O)C3=C(C=CC=C3O2)O

Technology Process of 5-Hydroxy-3'-methoxyflavone

There total 4 articles about 5-Hydroxy-3'-methoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

: C₁₈H₁₈O₅

: 6697-60-5
5-hydroxy-2-(3-methoxyphenyl)-chromen-4-one

Guidance literature:: With iodine; In dimethyl sulfoxide; at 160 ℃; for 0.333333h;
DOI:10.1016/j.ejmech.2017.02.037

Reference yield:

: 78646-28-3
2′-hydroxy-6′-methoxymethoxyacetophenone

: 6697-60-5
5-hydroxy-2-(3-methoxyphenyl)-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / 0 - 20 °C

2: iodine / dimethyl sulfoxide / 0.33 h / 160 °C

With iodine; potassium hydroxide; In ethanol; dimethyl sulfoxide;
DOI:10.1016/j.ejmech.2017.02.037

Reference yield:

: 699-83-2
2,6-dihydroxylacetophenone

: 6697-60-5
5-hydroxy-2-(3-methoxyphenyl)-chromen-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 4.5 h

2: potassium hydroxide / ethanol / 0 - 20 °C

3: iodine / dimethyl sulfoxide / 0.33 h / 160 °C

With iodine; N-ethyl-N,N-diisopropylamine; potassium hydroxide; In ethanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.ejmech.2017.02.037