1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole

Base Information

Chemical Name:1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole
CAS No.:142617-98-9
Molecular Formula:C₁₈H₁₉FN₄
Molecular Weight:310.374
Hs Code.:2933990090
ChEMBL ID:CHEMBL302743
DSSTox Substance ID:DTXSID60599905
Nikkaji Number:J1.572.718G
Pharos Ligand ID:VR75SY3N2F8Y
Wikidata:Q82495868
Mol file:142617-98-9.mol

Synonyms:1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole;142617-98-9;1-(4-FLUOROBENZYL)-2-(PIPERAZIN-1-YL)-1H-BENZO[D]IMIDAZOLE;CHEMBL302743;1-(4-Fluorobenzyl)-2-(piperazin-1-yl)-1H-benzimidazole;1-[(4-fluorophenyl)methyl]-2-piperazin-1-ylbenzimidazole;C18H19FN4;SCHEMBL7431298;DTXSID60599905;BDBM50103069;MFCD00915966;AB07683;DB-258823;CS-0446321;1-[(4-Fluorophenyl)methyl]-2-(piperazin-1-yl)-1H-benzimidazole;1-[(4-fluorophenyl)methyl]-2-(piperazin-1-yl)-1H-1,3-benzodiazole

Suppliers and Price of 1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-[(4-Fluorophenyl)methyl]-2-(piperazin-1-yl)-1H-1,3-benzodiazole 97%
1 g
$ 1000.00

SynQuest Laboratories
1-[(4-Fluorophenyl)methyl]-2-(piperazin-1-yl)-1H-1,3-benzodiazole 97%
250 mg
$ 493.00

J&W Pharmlab
1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole 96%
250mg
$ 325.00

American Custom Chemicals Corporation
1-(4-FLUOROBENZYL)-2-(PIPERAZIN-1-YL)-1H-BENZIMIDAZOLE 95.00%
1G
$ 1673.60

Total 8 raw suppliers

Chemical Property of 1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole

Chemical Property:

PSA：33.09000
LogP:3.02710
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:310.15937479
Heavy Atom Count:23
Complexity:379

Purity/Quality:

97% ^*data from raw suppliers

1-[(4-Fluorophenyl)methyl]-2-(piperazin-1-yl)-1H-1,3-benzodiazole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F

Technology Process of 1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole

There total 1 articles about 1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7191-70-0
N-(4''-fluorobenzyl)-1,2-phenylenediamine

: 142617-98-9
1-(4-fluorophenylmethyl)-2-(1-piperazinyl)-1H-benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide / 2 h / 60 °C

2: 1-methyl-pyrrolidin-2-one / 1 h / 180 °C / Microwave irradiation

With sodium hydride; In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2017.10.004